Glabridin 20% 40% 90% 98% CAS 59870-68-7 Glycyrrhiza Glabra

Min.Order: 1
Product origin: Baoji, Shaanxi, China
Infringement complaint: complaintComplaint
US$ 120

Description
Product Name 
Glabridin is a kind of flavonoids extracted from a precious plant called glabridin. Because of its powerful whitening effect, Guangglycyrrhizin is known as "whitening gold", which can eliminate free radicals and melanin in the bottom of the muscle, and is a holy thing for skin whitening and anti-aging.
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Flavonoid Function 
The yellowing of licorice extract is mainly caused by its flavonoids, and it also has other effects. The flavonoid components in licorice root have antispasmodic effects. Licorice flavonoids are the main flavonoid components with anti-inflammatory activity. These flavonoids have antioxidant and liver protective effects. The results of preclinical trials showed that flavonoids can kill most of the Helicobacter pylori bacteria that cause gastric ulcers and enteritis.
In medicine, licorice has sedative, diuretic, soothing, expectorant, relaxing, and phytoestrogenic effects. Traditionally, licorice is mainly used to treat asthma, bronchitis, fever, and tumors.
It has been widely used for the treatment of coughs, colds, and emergency treatment of the digestive system. Doctors in Japan use licorice to treat chronic hepatitis. Glycyrrhizic acid (glycyrrhizin) in licorice interferes with the surface antigen of hepatitis B and works with interferon to resist hepatitis A virus, and licorice can also be used to treat hepatitis C. Glycyrrhizin is 50 times sweeter than sucrose and can be used as a sweetener in food.
Glabridin (whitening gold)  (Glycyrrhizin whitening essence PT-40) can penetrate into the skin and maintain high activity, whiten and effectively resist oxidation. Effectively inhibit the activity of various enzymes in the process of melanogenesis, especially tyrosinase activity. At the same time, it also has anti rough skin and anti-inflammatory and antibacterial effects. Glabridin is a whitening ingredient with good efficacy and comprehensive functions. Glabridin is a whitening cosmetic additive launched by MARUZEN Company in 1989. After years of use, the effect is obvious and the safety is good. It is the main functional ingredient of high-end whitening cosmetics internationally. In addition to being widely used by cosmetics companies in Japan and South Korea, Lancome, Dior, SPA, and Chanel also commonly use this ingredient.
Application of glabridin in cosmetics: 1. Whitening, inhibiting melanogen; 2. Anti inflammation; 3. Antioxidant.
Glabridin, a hydrophobic component in licorice extract, has a good anti-inflammatory and whitening effect. Glycyrrhizin and glycyrrhetinic acid also have anti-inflammatory effects. These hydrophobic components include glycyrrhizin and other flavonoids, which have the effect of inhibiting melanin. The inhibitory activity of glabridin on melanin production has been tested in vivo and in vitro.
1. Inhibition of tyrosinase
Human tyrosinase is an essential enzyme that can regularly produce melanin, causing the skin or eyes to turn from brown to black. We know that skin exposure to ultraviolet light can cause some reactions (such as inflammation). Due to the destruction of the phospholipid membrane of skin tissue by reactive oxygen species induced by ultraviolet light, this histological change manifests as erythema and pigmentation. Reactive oxygen species are substances that can cause skin pigmentation, so inhibiting their production can inhibit the production of melanin. Glabridin is the most expensive and effective whitening ingredient among all whitening ingredients. According to the Chinese Materia Medica, glabridin's whitening effect is 232 times higher than ordinary vitamin C, 16 times higher than hydroquinone, and 1164 times higher than "arbutin", so glabridin is called "whitening gold".
2. Anti inflammatory effects
The anti-inflammatory activity of glabridin was verified through experiments. Pigmentation was caused by ultraviolet irradiation on guinea pigs, and then 0.5% glabridin solution was applied. It was found that glabridin alleviated skin inflammation caused by ultraviolet stimulation. Use a value to represent erythema on the skin. The degree of inflammation relief can be calculated by recording a value (colorimeter reading) of glabridin before and after irradiation. The researchers studied the inhibition of cyclooxygenase activity by glabridin. Cyclooxygenase is an enzyme that converts arachidonic acid into prostaglandins, which are just proinflammatory factors. Compared with the control group (using the current cyclooxygenase inhibitor, indomethacin), glabridin can achieve the effect of inhibiting cyclooxygenase. It is believed that glabridin can affect the production of arachidonic acid by inhibiting cyclooxygenase, thereby reducing inflammation.
3. Antioxidant effect
Glabridin has a strong scavenging effect on free radicals, including vitamin C, vitamin E and β- Carotene is recognized as the three king of anti-aging and anti-aging. glabridin is a natural antioxidant with the anti-aging capacity equivalent to vitamin E. It is reported that its antioxidant effect is significantly better than BHA and BHT. [3] There are literature reports that licorice can be used as a corticosteroid to reduce infectious skin diseases and enhance the effects of steroids.
4. Cosmetics application
Glabridin has excellent anti-inflammatory, antioxidant and anti melanin formation effects, so it is used as a component of various cosmetics and medical care products (such as face cream, lotion, shower gel, etc.). It can be made into whitening face cream, and such patented products have been launched.
Dosage: In cosmetics, in order to achieve whitening effect, the recommended dosage of patent is 0.001-3% glabridin, preferably 0.001-1%. Add glycerol 1:10 at low temperature. External application of glabridin can inhibit the formation of melanin. It has excellent tyrosinase inhibitory activity and can prevent skin tanning, line spots and sunburn. The recommended dosage is 0.0007-0.05%. The research shows that as long as 0.05% glabridin, 0.3% aloe powder, 1% nicotinamide and 1% AA2G are paired, the inhibition rate of melanin complexinase is as high as 98.97%. If it is to inhibit male hormones and treat acne, the dosage of glabridin is 0.01-0.5%.
Chinese scientists also studied the preparation of glabridin liposome and its application in cosmetics. The results showed that glabridin liposomes could be successfully prepared by liposome model and preparation technology. The Lipid bilayer membrane of glabridin liposome is similar to the biomembrane, which is easy to fuse with the biomembrane, promotes the penetration of the functional components to the biomembrane, makes the functional components cross the skin barrier and have a high transport efficiency of the biomembrane, and plays a positive role in improving and improving the skin whitening and freckle removing effect and other auxiliary effects.
Packing and Shipping
Delivery time :Within 3~10 working days after receiving the confirmed payment
MOQ : 1KG
Net Weight : 25kgs/Drum
Gross Weight : 28kgs/Drum
Payment :T/T,paypal or Alibaba Payment,If you need other payment methods, please contact us.
Freight : The freight cost will charge according to the destination detailed quantity.
Storage : Stored in dry and cool place, keep away from strong light and heat.
Shelf Life :Two years when properly stored.

OUR SERVICE
 1. We inspect the manufacture process strictly and the quality can be controlled.
 2. We supply high quality products, reasonable price, prompt delivery.
 3. Our products are natural,pure and no additives. 
 4. Free Sample To Test Quality First is Accepted.
 5. Our products can be OEM,packaging can be done according to the yours requirements.
 6. After SalServices24*7.

FAQ:
1.What's the min order for the usual?
  15kg. As for the high-value products, min order starts from 1g or 10g.
 
2.What's the sample cost?
  Free samples for normal products. Will charge on high-value products like huperzine-A.
 
3.What's the package and payment terms?
  We pack with 2 layers of food-grade plastic bags inside and aluminum foil bag outside, 10-25kg/drum.And payment terms are normally T/T & Western Union. 
 
4.What's the shipping time?
  May take 3-5 working days to Asia or surrounding countries by EMS etc..
  5~10 working days to European or Americ countries by EMS etc..
 
5.How do we do if the goods doesnt match with the sample?
  Usually we'll confirm the testing method, if it is because of the quality, we''ll recalled the unquality goods and send free the products to you again. Please don't worry, our products were tested before the shipping.

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