Product Name | 99% Cimetidine 51481-61-9 |
CAS | 51481-61-9 |
Appearance | White powder |
Molecular formula | C10H16N6S |
Molecular Weight | 252.34 |
Assay | 99%min, 98.0% --101.0% |
Shelf Life | 24 months when properly stored |
Storage | Keep in a cool, dry, dark location |
Chemical Properties | White Solid |
Uses | antibacterial |
Uses | Competitive histamine H2-receptor antagonist which inhibits gastric acid secretion and reduces pepsin output |
Definition | ChEBI: A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H -receptor antagonist that inhibits the production of acid in stomach. |
Indications | Cimetidine, the first released H2-blocker, like histamine, contains an imidazole ring structure. It is well absorbed following oral administration, with peak blood levels 45 to 90 minutes after drug ingestion. Blood levels remain within therapeutic concentrations for approximately 4 hours after a 300-mg dose. Following oral administration, 50 to 75% of the parent compound is excreted unchanged in the urine; the rest appears primarily as the sulfoxide metabolite. |
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