Cosmetic Peptide P21 Synthesis 98% Peptides AC-Dggl-Nh2 Powder

Min.Order: 1
Product origin: Wuhan, Hubei, China
Infringement complaint: complaintComplaint
US$ 350 ~ 450

Description

cosmetic Peptide P21 Synthesis 98% Peptides powder Ac-DGGL-NH2

P21 Lyophilized powder is available too
10mg*10 vials per bo





Physical Characters and specifications

Product nameP21 peptide
Sequence Ac-DGGL(A)G-NH2
CAS No.N/A
Molecular FormulaC30H54N6O5
Molecular weight579.3
Source Synthetic 
Purity98% min
 

Description:

Researchers found that the main neurogenic and memory enhancing effects from Cerebrolysin were due to its ability to react to human CNTF. So the researchers narrowed their search, and found that an 11-mer peptide, labeled peptide 6 (Ac-VGDGGLFEKKL-NH2), enhanced hippocampus-dependent learning and memory, increased neurogenesis, and neuronal plasticity. They then determined the most active sub-sequence in the peptide called peptide 6C (Ac-DGGL-NH2). However, this peptide sequence showed to have poor blood brain barrier permeability, and was easily broken down by plasma enzymes. To combat this, they added an adamantane moiety to the N-terminus of the peptide sequence. This highly lipophilic tricyclic alkane greatly increased the BBB permeability, and protected the peptide from enzymatic degredation. 



 
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