Quick detail:
Product Name: | Fluconazole |
Synonyms: | FLUCONAZOLE;FLUCONAZOLE-D4;FLUCONAZOLE-D4 (BISMETHYLENE-D4);diflucan;2,4-DIFLUORO-ALPHA, ALPHA-1-BIS(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZYL ALCOHOL;2,4-DIFLUORO-,1-BIS(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZYL ALCOHOL;A-(2,4-DIFLUOROPHENYL)-A-(1H-1,2,4-TRIAZOL-1-YLMETHYL)-1H-1,2,4-TRIAZOL-1-ETHANOL;alpha-(2,4-difluorophenyl)-alpha-(1h-1,2,4-triazol-1-ylmethyl)-1h-1,2,4-triazole-1-ethanol |
CAS: | 86386-73-4 |
MF: | C13H12F2N6O |
MW: | 306.27 |
EINECS: | 200-659-6 |
Product Categories: | Active Pharmaceutical Ingredients;Antibiotic Explorer;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;API's;Antifungal;Aromatics;Heterocycles;Pfizer compounds;Isotope Labelled Compounds;DARICON |
Melting point | 138-140°C |
storage temp. | −20°C |
solubility | DMSO: 5 mg/mL |
Description:
Fluconazole is used to treat serious fungal or yeast infections, such as vaginal candidiasis, oropharyngeal candidiasis (thrush, oral thrush), esophageal candidiasis (candida esophagitis), other candida infections (including urinary tract infections, peritonitis [inflammation of the lining of abdomen or stomach], and infections that may occur in different parts of the body), or fungal (cryptococcal) meningitis. This medicine works by killing the fungus or yeast, or preventing its growth.
Fluconazole is also used to prevent candidiasis in patients having bone marrow transplants who receive cancer or radiation treatment.
Usages:
Fluconazole is an azole antifungal. It kills sensitive fungi by interfering with the formation of the fungal cell membrane.
COA:
PRODUCT NAME:FLUCONAZOLE EP5.6 EXPIRY DATE:3 years CAS NO.: | ||
TEST ITEM | LIMT | TEST RESULTS |
APPEARANCE | WHITE OR ALMOST WHITE,HYGROSCOPLE,CRYSTALLINE POWDER | CONFORMS |
SOLUBILITY | SLIGHTLY SOLUBLE IN WATER,FREELY SOLUBLE IN METHANOL,SOLUBLE IN ACETONE | COMPLIES |
IDENTIFICATION | TO COMPLY | COMPLIES |
APPEARANCE OF SOLUTION | THE SOLUTION IS CLEAR AND COLORLESS | COMPLIES |
RELATED SUBSTANCES % | IMPURITY A≤0.4 IMPURITY B≤0.3 IMPURITY C≤0.1 UNSPECIFIED IMPURITIES≤0.1 TOTAL IMPURITY≤0.6 | 0.3 NIL NIL 0.02 0.32 |
HEAVY METALS % | ≤0.001 | <0.001 |
LOSS ON DRYING % | ≤0.5 | 0.18 |
SULPHATED ASH % | ≤0.1 | <0.1 |
ASSAY (ON DRY BASIS) % | 99.0-101.0 | 99.68 |
GRANULE SIZE | 180 MICRON MAX | CONFORMS |
CONCLUSION | CONFORMS TO EP5.6 |
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