Complaint
Tranexamic acid is a synthetic derivative of the amino acid lysine.Tranexamic acid is often prescribed for excessive bleeding.
Tranexamic acid is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, a molecule responsible for the degradation of fibrin. Fibrin is the basic framework for the formation of a blood clot in hemostasis.Tranexamic acid has roughly 8 times the antifibrinolytic activity of an older analogue, aminocaproic acid.
Item | Specification | Result |
Description | White crystalline powder
| Conform |
Identification | IR test
| Conform |
PH | 7.0~8.0 | 7.4 |
Related substances Liquid chromatography
| ImpurityA ≤0.1% ImpurityB≤0.2% Any other impurity≤0.1% All other impurity≤0.2% | <0.1% <0.2% <0.1% <0.2% |
Loss on drying | ≤0.5% | 0.3% |
Residue on ignition | ≤0.1% | <.08% |
Heavy metals | ≤10ppm | <10ppm |
Chlorides | ≤14ppm | <140ppm |
Sulphated ash | ≤0.1% | <0.1% |
Assay | 99.0%~101.0% | 99.76% |
