Antimalarial Artemether/Lumefantrine Tablets 20/120mg GMP Cetificated

Min.Order: 5,000

Product origin: Wuhan, Hubei, China

Infringement complaint:

Complaint

US$ 0.5 ~ 0.7

Description

Product name: Artemether+Lumefantrine Tablets

PACKING:

Artemether 20mg + Lumefantrine 120mg	24tablets/blister/box
Artemether 20mg + Lumefantrine 120mg	6tabletsX 4blisters/box
Artemether 40mg+ Lumefantrine 240mg	6tabletsX 2blisters/box
Artemether 80mg + Lumefantrine 480mg	6tablets/blister/box

Pharmacodynamics:
The combination of artemether and lumefantrine is used to treat certain kinds of malaria infections (a serious infection that is spread by mosquitoes in certain parts of the world and can cause death). Artemether and lumefantrine should not be used to prevent malaria. Artemether and lumefantrine is in a class of medications called antimalarials. It works by killing the organisms that cause malaria.

Pharmacokinetics:
Orally administered Artemether is rapidly absorbed reaching therapeutic levels within 60-90 minutes. Artemether is metabolized in the liver to the demethylated derivate dihydroartemisinin (DHA). The elimination is rapid, with a T 1/2 of 2-4 hours. Dihydroartemisinin, being a potent antimalarial itself, has a T 1/2 of 2-4 hours. The degree of binding to plasma proteins varies markedly according to the species studied. The binding of Artemether with plasma protein in man is about 50%. Radioactivity distribution of Artemether was found to be equal between cells and plasma.
The absorption of Lumefantrine is highly influenced by lipids and food intake (from 10% by fasting to 100% at normal diet). Therefore patients should be encouraged to take the medication with some fatty food as soon as it can be tolerated.
Lumefantrine is N-debutylated in human liver microsomes . This metabolite has 5 to 8 fold higher antiparasitic effects than lumefantrine. Lumefantrine is found to be highly protein bound (95%). The elimination half life in malarial attaint patients will be 4 to 6 days. Lumefantrine and its metabolites are found in bile and faeces.

How should this medicine be used?
The combination of artemether and lumefantrine comes as a tablet to take by mouth. It is usually taken twice a day for 3 days as instructed by your doctor. Always take artemether and lumefantrine with food. If you are not able to eat, contact your doctor. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take artemether and lumefantrine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Weight(kg)	Tables/Dose(n)	Total Tablets(n)
5-15	1	6
15-25	2	12
25-35	3	18
≥35	4	24

Note: children and old people should take this medicine under the doctor's advice. It is forbidden to take this medicine for allergic people and pregnant women

CAUTION!