Complaint
| Introduction: | HA is a straight-train macromolecular glycosaminoglycan that is composed of the D-glucuronate and N-acetyl-D-aminoglucose disaccharide unit and is a kind of acid mucopolysacharide. It extensively exists in soft tissues such as cell matrix, vitreous body of eyes, ambilical cord, cartilage, skin and joint synovial fluid of human beings and animals. The commodity HA is usually in the sodium salt form and appears as white powder, particle or fibriform solid. It has strong hygroscopicity and dissolves in water, doesn't dissolve in organic solvent. |
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| Usage: | HA is extensively applied in fields of medicine, cosmetics and health food. |
| Date: | July 28, 2021 |
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| Batch No.: | 2021071415 |
| Quantity: | 153kg |
| Appearance: | White or almost white powder or granule. |
| Packaging: | Packed in a double-layer polyethylene bag that is placed in a fiber drum.The unit content is 25kg/drum |
| Items | Standard | Result |
|---|---|---|
| Glucuronic acid | ≥46% | 47.0% |
| Sodium hyaluronate | ≥95% | 97.2% |
| Appearance of Solution | A600nm≤0.01 0.01 | Complied |
| Nucleic Acids | A260nm≤0.5 | Complied |
| PH(0.5% aq.sol.,25ºC | 5.0-8.5 | 6.7 |
| Molecular weight | 0.80-1.50Million Daltons | 1.10 Million Daltons |
| Protein | ≤0.1% | 0.04% |
| Loss on drying | ≤10.0% | 6.9% |
| Residue on Ignition | ≤20.0% | 17.2% |
| Chlorides | ≤0.5% | Complied |
| Iron | ≤80ppm | <80ppm |
| Heavy metal | ≤20ppm | <2ppm |
| Arsenic | ≤2ppm | <2ppm |
| Bacteria Counts | ≤100CFU/G | Complied |
| Molds&Yeasts | ≤50CFU/G | Complied |
| Molds&Yeasts | ≤50CFU/G | Complied |
| Staphylococcus aureus | Negative/g | Negative/g |
| Escherichia coli | Negative/g | Negative/g |
| Hemolytic Streptococci | Negative/g | Negative/g |
| Salmonella | Negative/g | Negative/g |
| Conclusion | Conclusion:Complied with EP 9.0 |
