Complaint
| Product name | Midostaurin |
| CAS | 120685-11-2 |
| Appearance | white powder |
| Assay | 99% |
| Storage | Cool and Protect from light |
Product Name:Midostaurin
CAS:120685-11-2
MF:C35H30N4O4
MW:570.646
EINECS:999-999-2
Mol File:120685-11-2.mol
Melting point:235-260ºC
Density 1.47±0.1 g/cm3(Predicted)
storage temp. Store at 2-8
solubility Soluble in DMSO (15 mg/ml), MDC (10 mg/ml), methanole (5 mg/ml), 100% ethanol (2.5 mg/ml), and DMF (20 mg/ml).
form Tan solid
Function:
Midostaurin was shown to possess antiproliferative characteristics via inhibition of protein kinase C, kinase insert domain receptor, and c-kit.
DefinitionChEBI: An organic heterooctacyclic compound that is the N-benzoyl derivative of staurosporine.
Biological ActivityBroad spectrum protein kinase inhibitor. Inhibits conventional PKC isoforms ( α , β , γ ), PDFR β , VEGFR2, Syk, PKCη, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1 and EGFR. Displays potent antitumor activity.
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