Complaint
Product Details
CAS:61-12-1
MF:C20H30ClN3O2
MW:379.92
EINECS: 200-498-1
Product Categories:API;NUPERCAINAL;Other APIs;Amines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API
Melting point:99-101 °C(lit.)
density:1.1338 (rough estimate)
refractive index:1.5400 (estimate)
storage temp.:Refrigerator
color:Hygroscopic crystals
PH:pH(20g/l,25ºC) : 5.0~6.0
Water Solubility :Freely soluble in water, alcohol, aceton, or chloro form
Stability:Stable. Incompatible with strong oxidizing agents. Protect from moisture.
Uses:Cinchocaine is used as an anaesthetic agent for spinal anaesthesia; a component in rectal medications used in inflammation of the anus and for the symptomatic treatment of hemorrhoids and fissures in the anus; local anesthetic agent.
Dibucaine Hydrochloride is a local anesthetic of the amide type now generally used for surface anesthesia.
Sodium ChannelDibucaine is an amide local anesthetic.
Dibucaine reduced the degradation of BSA-gold complex in the reservosomes, which was not caused either by an inhibition of the whole proteolytic activity of the parasite or by a reduction on the expression levels of cruzipain [1].
Dibucaine, a quaternary ammonium compound, inhibited SChE to a minimum within 2 min in a reversible manner.
The inhibition was very potent. It had an IC(50) of 5.3 microM with BuTch or 3.8 microM with AcTch. The inhibition was competitive with respect to BuTch with a K(i) of 1.3 microM and a linear-mixed type (competitive/noncompetitive) with respect to AcTch with inhibition constants, K(i) and K(I) of 0.66 and 2.5 microM, respectively.
Dibucaine possesses a butoxy side chain that is similar to the butryl group of BuTch and longer by an ethylene group from AcTch.
1.applied in pharmaceutical field as pharmaceutical raw materials.
2.applied in health care product.
1.COA/MSDS/ROS/MOA Available.
2.Any inquiries will be replied within 12 hours.
3. Dedication to quality, supply & service.
4.Strictly on selecting raw materials.
5.Reasonable & competitive price, fast lead time.
6.Faster delivery:Sample order in stock and one week for bulk production.
7.We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
8.Timely after-service resolves your worry for internation trade.
9.Payment:
