Complaint
1. Characteristics of Hyaluronic Acid/Sodium Hyaluronate
Synonyms: HA/Hyaluronic Acid/Hyaluronic acid sodium salt
MOQ: 100G
Package: 100g/bag, 5KG/bag, 1KG/bag
HS Code: 3913900090
Certificate: ISO/Kosher/Halal
Grade: Cosmetic grade
Type: High, medium, low molecular weight and oligo HA
Application: Food/Cosmetic/Eye drops/Injection
Source: Natural Microbial fermentation
Bacteria: Streptococcus zooepidemicus
Certificate: GMP/ISO/Kosher/Halal/CEP
Assay: min. 95%
2. Sodium hyaluronate hyaluronic acid specification
Across Biotech supply oligo, low, medium, and high molecular weight hyaluronic acid(sodium hyaluronate) powder cosmetic/food/medical(eye drops/injection) grade for sale.
The molecular weight ranges: oligo 3-5K, oligo 7-10K, 10-100K, 0.1-0.5M, 0.5-0.8M, 0.8-1.5M, 1.5-2.0M, >2.0M.
Cosmetic grade HA specification
| Item | Specification |
| Appearance | White or almost white powder or granules |
| Infrared absorption | Positive |
| Reaction of sodium | Positive |
| Absorbance | ≤0.25 |
| Transparency | ≥99.0% |
| Ph | 6.0-7.5 |
| Instrinsic vscosity | 13.77-23.64 dl/g |
| Molecular weight | 0.8-1.5 MDa |
| Kinematic viscosity | Actual value |
| Purity test | |
| Loss on drying | ≤10% |
| Residue on ignition | ≤20% |
| Heavy metals | ≤20ppm |
| Arsenic | ≤2ppm |
| Protein | ≤0.1% |
| Assay | ≥95.0% |
| Glucuronic acid | ≥46.0% |
| Microbiological test | |
| Total bacterial count | ≤100 CFU/g |
| Mold & Yeasts | ≤20 CFU/g |
| E.coli | Negative |
| Staph | Negative |
| Pseudomonas aeruginosa | Negative |
| Salmonella | Negative |
Food grade HA specification
| Item | Specification |
| Appearance | White or almost white powder or granules |
| Infrared absorption | Positive |
| Reaction of sodium | Positive |
| Bulk density | ≥0.2g/cm3 |
| Absorbance | ≤0.25 |
| Transparency | ≥99.0% |
| Ph | 6.0-7.5 |
| Instrinsic vscosity | 13.77-23.64 dl/g |
| Molecular weight | 0.8-1.2 MDa |
| Kinematic viscosity | Actual value |
| Mesh | ≥60 |
| Purity test | |
| Loss on drying | ≤10% |
| Residue on ignition | ≤20% |
| Heavy metals | ≤20ppm |
| Arsenic | ≤2ppm |
| Cadmium | ≤0.2ppm |
| Mercury | ≤0.1ppm |
| Lead | ≤0.5ppm |
| Protein | ≤0.1% |
| Assay | ≥95.0% |
| Glucuronic acid | ≥46.0% |
| Microbiological test | |
| Total bacterial count | ≤100 CFU/g |
| Mold & Yeasts | ≤20 CFU/g |
| E.coli | Negative |
| Staph | Negative |
| Pseudomonas aeruginosa | Negative |
| Salmonella | Negative |
Eye drops grade HA specification
| Item | Specification |
| Appearance | White or almost white powder or granules |
| Infrared absorption | Positive |
| Reaction of sodium | Positive |
| Appearance of solution | Clear and the absorbance is NMT 0.01 at 600 nm |
| Ph | 5.0~8.5(0.5% solution) |
| Intrinsic viscosity | Actual value |
| Purity test | |
| Nucleic acids | The absorbance is NMT 0.5 at 260 nm |
| Chlorides | ≤0.5% |
| Loss on drying | ≤20% |
| Iron | ≤80ppm |
| Residual solvents(Ethanol) | ≤5000ppm |
| Protein | ≤0.1% |
| Assay | ≥95.0% |
| Bacterial endotoxins | ≤0.5 IU/g |
| Microbiological test | |
| Total bacterial count | ≤100 CFU/g |
| Mold & Yeasts | ≤20 CFU/g |
| E.coli | Negative |
| Staph | Negative |
| Pseudomonas aeruginosa | Negative |
| Salmonella | Negative |
Injection grade HA specification
| Item | Specification |
| Appearance | White or almost white powder or granules |
| Infrared absorption | Positive |
| Reaction of sodium | Positive |
| Appearance of solution | Clear and the absorbance is NMT 0.01 at 600 nm |
| Ph | 5.0~8.5(0.5% solution) |
| Instrinsic vscosity | 13.77-23.64 dl/g |
| Molecular weight | 0.8-1.5 MDa |
| Kinematic viscosity | Actual value |
| Purity test | |
| Nucleic acids | The absorbance is NMT 0.05 at 260 nm |
| Chlorides | ≤0.5% |
| Loss on drying | ≤20% |
| Iron | ≤80ppm |
| Residual solvents(Ethanol) | ≤5000ppm |
| Protein | ≤0.1% |
| Assay | ≥95.0% |
| Bacterial endotoxins | ≤0.05 IU/g |
| Microbiological test | |
| Total bacterial count | ≤100 CFU/g |
| Mold & Yeasts | ≤20 CFU/g |
| E.coli | Negative |
| Staph | Negative |
| Pseudomonas aeruginosa | Negative |
| Salmonella | Negative |
| Item | |
| Food Grade Sodium Hyaluronate | |
| Cosmetic Grade Sodium Hyaluronate | |
| Eye Drops Grade Sodium Hyaluronate | |
| Injection Grade Sodium Hyaluronate |
The molecular weight ranges: oligo 3-5K, oligo 7-10K, 10-100K, 0.1-0.5M, 0.5-0.8M, 0.8-1.5M, 1.5-2.0M, >2.0M.
Clients visiting; Manufacturer audit; Factory tour.
Across Biotech has been supplying "food and feed additives". We are located in Jinan, Shandong province, a beautiful historic city, about 3 hours' driving from Qingdao port. Our own warehouse allows us to respond to customers' inquiries in the first instance and deliver products quickly.
We focus on food and feed additives, The main products are vitamins, preservatives, sweeteners, acidifiers, flavorings, thickeners, amino acids, phosphates, nutrition enhancers, feed premix OEM and etc. We have also made an inventory of some products so that we can deliver the goods in time to ensure the normal supply of the goods.
1. We understand the industry, the competitive landscape of the product, the current state of production, and the characteristics of the product.
2. We not only provide products but also provide the latest industry information and product dynamics, saving you manpower and production costs.
3. We set up the warehouse near the logistics center to ensure that the products respond quickly and are sent out first.
4. Selection of shipping methods according to customer requirements. Documents, and files, were perfected in time and sent to the customer.
