Crizotinib Raw Material CAS 877399-52-5 Pharmaceutical Intermediate Crizotinib
Product Name | Crizotinib Raw Material CAS 877399-52-5 Pharmaceutical Intermediate Crizotinib |
Apperance | white powder |
CAS | 877399-52-5 |
Molecular formula | C21H22Cl2FN5O |
Molecular Weight | 450.34 |
Extraction Type | Solvent Extraction |
Specification Available | HPLC 98% |
Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. |
Shelf Life | 24 Months |
Crizotinib Raw Material CAS 877399-52-5 Pharmaceutical Intermediate Crizotinib
Crizotinib (XalkoriR), chemically known as 3-[(R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine,
is a white to light yellow powder. It is primarily useful for the treatment of patients with locally advanced or metastatic non-small
cell lung cancer (NSCLC) who are positive for mesenchymal lymphoma kinase (ALK) as determined by an SFDA-approved assay.
Crizotinib capsules can be used for the treatment of patients with locally advanced or metastatic non-small cell
lung cancer (NSCLC) who are positive for mesenchymal lymphoma kinase (ALK) as determined by an SFDA-approved
assay. Approval for this indication is based primarily on objective remission rate (ORR) and progression-free survival
(PFS) evidence, and no evidence of survival benefit (OS) is currently available for this product.