OC-000459; OC 000459;[5-Fluoro-2-methyl-3-(2-quinolinylmethyl)-1H-indol-1-yl]acetic acid;5-Fluoro-2-methyl-3-(2-quinolinylmethyl)-1H-indole-1-acetic acid.
OC-000459 for the treatment of hair loss dwindled, perhaps due more to commercial potential and chemical stability reasons than efficacy as the later studies of OC000459 have focused on different chemical forms of the drug and combining it with various nanoparticles to enhance delivery. Recent years have seen the odd study pop up in relation to OC000459 and the treatment of acne and prostate cancer, which are conditions also driven by, however, the most recent study published in relation to OC000459 was back in 2008.
OC000459 is a non-steroidal anti-androgen drug, which competes with DHT for binding at the receptors where it causes hirsutism or hair loss. It has been evaluated as being approximately equivalent in strength to hydroxyflutamide, a drug which is sometimes used in PCOS to treat hirsutism or androgenetic alopecia. One study in 1998 concluded.
COA:
Item | Specification |
Specific rotation | +39.5 to +41.5° |
State of solution(transmittance) | Clear 98.0% min. |
Chloride[cl] | 0.020% max. |
Ammonium [NH4] | 0.02% max. |
Sulfate[SO4] | 0.020% max |
Iron[Fe] | 10ppm max. |
Heavy metals [Pb] | 10ppm max |
[As2O3] | 1ppm max |
Other amino acids | Chromatographically not detectable |
Loss on drying | 0.20% max. |
Residue on ignition[sulfated] | 0.10% max. |
Assay | 99.0% min |
Company Introduction
Wuhan HaileruiTechnology Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.
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Hair Loss Treatment USP Standard Seripiprant Raw Powder Oc000459 CAS 851723-84-7