Complaint
| Product Name: | Creatine Phosphate sodium |
| Appearance | White powder |
| Specification | 98% |
| CAS | 71519-72-7 |
| Package | 5kg/barrel |
| Sample | Availiable |
| Storage | Dry Place |
| Shelf life | 2 Years |
Functions of Creatine Phosphate Sodium:
Creatine Phosphate Sodium is a kind of myocardium protective agent widely distributed in body tissue. 90% of them are in muscular tissue to maintain ATP level. It is used for prevention and cure of heart paralysis. It is also suitable for myocardial ischemia, cardiac hypertrophy, myocardial infarction and congestive heart failure.
Application of Creatine Phosphate Sodium:
(1) Myocardial protective agent
Creatine Phosphate Sodium is widely distributed in the body tissues, 90% in muscle tissue, creatine phosphate is used to maintain ATP levels. Phosphocreatine synthesis pathway through open reduction and decomposition, muscle fiber membrane protection against ischemic damage and maintaining the nuclear acid reservoir cells. Clinic for heart disease protection cardioplegia myocardial metabolism and other health distress. Suitable for myocardial ischemia, hypertrophy, myocardial infarction and heart failure treatment (adjuvant therapy). It can also be used for various cardiac surgery.
(2)Buffer the acidic substance sudden increase in muscle
(3) Creatine phosphate (CP) is also involved in energy transport
That carries the energy from the mitochondria to other parts of the muscle.
(4) Athletes preferred transport supplements
Creatine Phosphate for increasing physical fitness of athletes to improve athletic performance had a significant effect, safe and effective, no side effects. During the competition, increase creatine phosphate (CP) levels can improve the training and competition results.
(5) ATP's
Phosphocreatine can transfer high-energy phosphate to ADP to generate ATP, creatine phosphate is therefore stored in the form of ATP.
(6) The effect of ADP to produce ATP
When creatine phosphokinase reduced to zero before, when brain tissue hypoxia, creatine phosphate and ADP action can generate ATP.
(7) Buffer
In addition to providing energy creatine phosphate, but in high-intensity exercise can also control the muscles of the acidic substance acts as buffer. This is because creatine phosphate in the synthesis of ATP during high-intensity exercise need to consume in the accumulation of lactic acid in the muscles release hydrogen ions, hydrogen ions and muscles too much will hinder muscle contraction, so creatine phosphate can serve as buffers and delays fatigue appears.
(8) Phosphocreatine also stimulate growthhormone secretion
So that products taurine and creatine phosphate synthesis to promote mutual cooperation be strengthened in there with adequate protein or amino acid supplement the premise of better muscle protein synthesis rate and effect.
| Testing terms | Specifications | Results |
| Identification | White or almost white powder or crystalline powder; moisture induction | White powder |
| Phosphate Reaction | (1)Take this product,add water to dissolve,Add ammonium molybdate test solution and dilute nitric acid,water bath heating to produce ; yellow precipitation.separation. precipitation can be dissolved in ammonia test solution.. | Positive |
| IR | (2)The infrared absorption spectrum of this product should be consistent with that of the control product. | Conforms |
| Liquid Chromatogram | (3)In the chromatogram recorded under the content determination,the retention time of the main peak of the test solution should be the same as that of the control solution. | Conforms |
| Sodium | (4)This product shows the reaction of sodium salt identification(1) | Postive |
| Appearance of Soluion | The solution should be clear and colorless | clear and colorless solution |
| pH | 8.0 to 9.0 | 8.4 |
| Related Substances | Calculated by peak area acording to extemal method,Contains not more than 0.5% of Creatine,Creatinine and Sodium creatinine phosphate, respectively; Contains not more than 0. 10% of Creatine diphosphate;Any other individual unspecified impurity is not more than 0.2 times the principal peak in reference solution (0.10 perccnt); The total impurity is not more than 2.0% | Creatine%: 0.2% Creatinine%: Not detected Sodium creatinine phosphate%: 0.03% Creatine diphosphate%: Not detected Any other individual unspecified impurity%: 0.033% The total impurity%: 0.26% |
| Chloride | ≤0.02% | <0.02% |
| Arsenic | ≤0.0001% | <0.0001% |
| Molysite | ≤0.001% | <0.001% |
| Barium | Visual inspection, both liquids should be equally clarified | Both liquids are equally clarified |
| Heavy Metal | <0.001% | < 0.001% |
| Water Content | 22.0 percent to 25.0 percent | 24.5% |
| Ethanol | ≤0.5% | Not detected |
| Visible Particle | Take this product, it meet there quirements, according to the method of Visible Particulate Matter | Conforms |
| Subvisible Particle | Take 4 pieces of this product, Add 10ml of water for particle inspection, No more than 6000 particles> 10 μum in each branch, No more than 600 particles> 25 um in each branch, according to the method of Subvisible Particulate Matter | ≥l0μm in each branch: 77 particles ≥25μm in each branch:10 paricles |
| Abnormal toxicity | Should comply with the regulations | Conforms |
| Sterility | Take this product add 0. 1% sterile peptone solution to dissolve, Dilute to make a solution containing about 10mg of sodium creatine phosphate per lml, Membrane Filtation, Rinse with 0.1% sterile peptone aqueous solution, No less than 300ml per membrane, comply with the regulations | Conforms |
| Bacterial Endotoxins | Contains not more than 0.15 Endotoxin Unit/mg of Creatine Phosphate Sodium | <0.15EU/mg |
| Assay | It contains NLT 98.0% of the labeled amount of Creatine Phosphate Sodium (C4H8N3Na2O5P), calculated according to anhydrous and solvent-free substance. | 99.2% |
| Conclusion | The results conform with Ch.P 2020 Vol.4 and STP-X-QQ-QC-008 | |
