Description
High Quality Pharmaceutical Raw Material Abemaciclib Powder CAS 1231929-97-7 Abemaciclib For Anti-tumor
| Product Name | High Quality Pharmaceutical Raw Material Abemaciclib Powder CAS 1231929-97-7 Abemaciclib For Anti-tumor |
| Appearance | white powder |
| CAS | 1231929-97-7 |
| Assay | 99% |
| Keywords | Abemaciclib;Abemaciclib Powder;Abemaciclib CAS 1231929-97-7 |
| Shelf Life | 24 months when properly stored |
| Storage | Keep in a cool, dry, dark location |
| What is Abemaciclib?
Product name: LY2835219; Abemaciclib; Bemaciclib
CAS No.: 1231929-97-7
MF: C27H32F2N8
MW: 506.5933864
Appearance: White powder
Standard: 99%min.
Lead time: Immediate delivery
Packing: 1kg/Al-foiled bag |
Function of AbemaciclibAbemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers.
Abemaciclib is a CD4/6 kinase inhibitor. This type of kinase is activated by connecting D-cyclin. In breast cancer cell lines that are estrogen receptor positive (HR+), cyclin D1 and CD4/ 6 It can bind to phosphorylation of retinoblastoma protein (Rb), cell cycle progression and cell proliferation. In vitro, continuous exposure to Abemaciclib inhibits Rb phosphorylation and prevents entry from G1 into the S phase of the cell cycle, leading to cell senescence and apoptosis. In breast cancer xenotransplantation models, Abemaciclib monotherapy or combined with anti-estrogens can be administered continuously every day to shrink tumors. Application of AbemaciclibAbemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers.Pharmaceutical Best price Raw Material Abemaciclib CAS 1231929-97-7 Abemaciclib Powder »»» CLICK HERE TO SEE MORE STOCK
Q: What's your MOQ ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low, price product, our MOQ starts from 100g and 1kg.
Q: Is there a discount ?
A: Yes, for larger quantity, we always support with better price.
Q: How to confirm the Product Quality before placing orders ?
A: You can get free samples for some proucts, you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests, we will manufacture the products according to your requests.
Q: How to start orders or make payments ?
A: You can send our your Purchase order ( if your company has ), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q: How do you treat quality complaint ?
A: First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
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