Product Name | Azthromycin Dihydrate |
Brand Name | YYC |
Purity | 99% |
MF | C38H72N2O12 |
Appearance | White Powder |
Test Method | HPLC |
Azthromycin is an azalide macrolide antibiotic derived from erythromycin. Azthromycin binds the bacterial 50S ribosomal subunit, inhibiting protein translation. Azthromycin displays antibacterial, anti-fibrotic, and anti-inflammatory activities. In epithelial cells, azthromycin inhibits the epithelial-to-mesenchymal transition (EMT) by inhibiting expression of Smad3. Additionally, azthromycin inhibits production of arachidonic acid, eicosanoids, IL-6, and IL-12 in LPS-stimulated macrophages.