Product name | Peptide 6c |
Appearance | White powder |
Purity | 99% |
Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder. |
Shelf Life | 24 Months |
The researchers narrowed their search, and found that an 11-mer peptide, labeled peptide 6 (Ac-VGDGGL
FEKKL-NH2), enhanced hippocampus-dependent learning and memory, increased neurogenesis, and
neuronal plasticity.
They then determined the most active sub-sequence in the peptide called peptide 6C (Ac-DGGL-NH2).
However, this peptide sequence showed to have poor blood brain barrier permeability, and was easily broken
down by plasma enzymes.
To combat this, they added an adamantane moiety to the N-terminus of the peptide sequence. This highly
lipophilic tricyclic alkane greatly increased the BBB permeability, and protected the peptide from enzymatic
degredation.