Description
Edaravone is a new type of free radical scavenger, which was first listed in Japan in April 2001, and is mainly used in clinical treatment of ischemic stroke. Edaravone exists in the form of anion and can donate one electron to free radicals to achieve the purpose of scavenging free radicals. Because its molecular structure contains lipophilic groups, it can easily reach the brain tissue through the blood-brain barrier, and has a protective effect on nerve cell damage caused by cerebral ischemia. Mechanism of Action Edaravone's effect on nerve cell protection Chemicalbook's main mechanisms include scavenging oxygen free radicals, inhibiting lipid peroxidation, regulating inflammatory factors, and inhibiting apoptosis. With the in-depth study of edaravone, it was found that in addition to the treatment of acute cerebral ischemia, edaravone has therapeutic effects on other diseases of the nervous system that involve oxidative stress. In addition, edaravone has protective effects on other organs other than the nervous system. Edaravone is currently mainly used for the treatment of ischemic stroke, and has less clinical applications in other aspects.
Complaint
