Name : Folic Acid
Shape : Light Yellow crystalline powder
1. The breeding of pigs, cows and chickens
2. It is effective in preventing the occurrence of incomplete nerve closure in infants.
3. Elevated plasma homocysteine concentration will lead to thrombotic occlusive heart and cerebrovascular diseases, anorexia and anorexia nervosa, senile vascular dementia, depression and other diseases.Folic acid is an important cofactor in the cycling metabolism of homocysteine. After activation, folate can be converted to 5, 10-methylene tetrahydrofolate, which provides methyl for homocysteine to methionine.Folic acid deficiency causes a large amount of homocysteine to accumulate and discharge extracellular resulting in elevated plasma homocysteine concentration, leading to disease.Studies have shown that the consumption of folate fortified food has an essential relationship with the increase of serum folate level in middle-aged and elderly people.Folic acid may reduce the risk of gout in people who have no history of gout.Deficiency of folic acid can lead to multi-system damage, mainly colitis and chronic atrophic gastritis in the digestive system, and increase the risk of colon and stomach cancer.Folic acid supplements can inhibit the recurrence rate of colorectal cancer.
Folic acid is absorbed in the body in two ways: active absorption and diffusion passive absorption, mainly in the upper small intestine.The absorption rate of reduced folic acid is higher, the more glutamyl, the lower the absorption rate. Glucose and vitamin C can promote absorption.The absorbed folic acid is stored in the intestinal wall, liver, bone marrow and other tissues in the body, and is reduced by folate reductase with the participation of NADPH to tetrahydrofolate (THFA or FH4) with physiological activity, which participates in the synthesis of purines and pyrimidines.Therefore, folate plays an important role in protein synthesis, cell division and growth, and can promote the formation of normal red blood cells.Lack of red blood cell hemoglobin generation can be reduced, blocked cell maturation, resulting in megaloblyte anemia.
Name | CAS | molecular | density |
Folic Acid | 59-30-3 | C19H19N7O6 | 0.97 |