Mesna | CAS : 19767-45-4 | Brand:HNB |
MW: C2H5NaO3S2 | MSDS: Avaiable | |
MF : 164.17 | Sample: Avaiable | |
Category: Oncology drug | Min order: 10grams | |
Quality standard: USP | Place of Origin:China | |
Introduction | Mesna is an organosulfur compound. It is used in cancer chemotherapy involving cyclophosphamide and ifosfamide as an adjuvant. It is an acronym for 2-Mercaptoethane sulfonate Na (Na being the symbol for sodium). Mesna is used therapeutically to reduce the incidence of haemorrhagic cystitis and haematuria when a patient receives ifosfamide or cyclophosphamide for cancer chemotherapy. These two anticancer agents, in vivo, may be converted to urotoxic metabolites such as acrolein. It assists to detoxify these metabolites by reaction of its sulfhydryl group with the vinyl group. It also increases urinary excretion of cysteine | |
Character | White to off-white powder | |
Applications | Pharmaceutical raw materials , Oncology drug |
Indication:
Prevent urinary tract toxicity caused by cyclophosphamide, different cyclophosphamide, chlorine phosphorus amide medicines
Pharmacology:
This product is contained half glutathione amino acid compounds, can repeat activation cyclophosphamide with toxic or the daughter cyclophosphamide metabolites unifies, forming non toxic product which quickly out of body with urine.
Prevent urinary tract toxicity caused by cyclophosphamide, different cyclophosphamide, chlorine phosphorus amide medicines