Complaint
| Catalog No. | BS1945 |
|---|---|
| Product Name | AR-α2C (R369) polyclonal antibody |
| Applications | WB IHC IF |
| Alternative Name | Alpha-2C adrenergic receptor; Alpha-2 adrenergic receptor subtype C4; Alpha-2C adrenoreceptor; Alpha-2C adrenoceptor; Alpha-2CAR; ADRA2C; ADRA2L2; ADRA2RL2; α-2C adrenergic receptor; α-2 adrenergic receptor subtype C4; α-2C adrenoreceptor; α-2C adrenocept |
| Swiss-Prot | P18825 |
| Host | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Application_all | WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200 |
| Product | Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 |
| Purification&Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE). |
| Storage&Stability | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Specificity | AR α2C (R369) polyclonal antibody detects endogenous levels of AR α2C protein. |
| BiowMW | ~ 70 kDa |
| Note | For research use only, not for use in diagnostic procedure. |
| Immunogen | Synthetic peptide, corresponding to amino acids 340-390 of Human AR-α2C. |
Background
Alpha-2C adrenergic receptors (α2C-AR) regulate neurotransmitter release from sympathetic nerves in the heart, and from adrenergic neurons in the central nervous system. α2C-AR can influence Parkinson's disease, panic disorders, and Huntington disease (HD) progression. α2C-AR transcripts are present in rat muscle, heart, pancreas, and kidney.
