Product Name:Estradiol CAS:57-91-0 MF:C18H24O2 MW:272.38 EINECS:200-354-8 Mol File:57-91-0.mol Melting point:176-180 °C(lit.) alpha D20 +53 to +56° (c = 0.9 in dioxanie) Boiling point:355.44°C (rough estimate) Density 1.0708 (rough estimate) refractive index 1.4800 (estimate) storage temp. 0-6°C solubility ethanol: 50 mg/mL, clear, colorless pka10.27±0.60(Predicted) form powder color white with slight yellow cast Water Solubility 3.9mg/L(25 ºC)
Description White Solid UsesEstradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer's disease and ischemic stroke.
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