API CAS 70-18-8 Glutathione Raw Material Glutathione Pharmaceutical Grade Glutathione
Product Description
Product Details
Product Name
Glutathione
Appearance
white or off white powder
CAS NO.
70-18-8
Molecular Formula
C20H32N6O12S2
Molecular Weight
612.63
Glutathione (GSH) is named Reduced glutathione or L-GlutathioneReduced ,an important antioxidant in plants, animals, fungi, and some bacteria and archaea,a white crystalline powder. It is atripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side chain and the amine group of cysteine, and the carboxyl group of cysteine is attached by normal peptide linkage to a glycine.Thiol groups are reducing agents, existing at a concentration around 5 mM in animal cells. Glutathione reduces disulfide bonds formed within cytoplasmicproteins to cysteines by serving as an electron donor. In the process, glutathione is converted to its oxidized form, glutathione disulfide (GSSG), also called L-glutathione.
Application&Function
1.It maintains levels of reduced glutaredoxin and glutathione peroxidase. 2.It is one of the major endogenous antioxidants produced by the cells, participating directly in the neutralization of free radicals and reactive oxygen compounds, as well as maintaining exogenous antioxidants such as vitamins C and E in their reduced (active) forms. 3.It is used in metabolic and biochemical reactions such as DNA synthesis and repair, protein synthesis, prostaglandin synthesis,amino acid transport, and enzyme activation. It has a vital function in iron metabolism. Yeast cells depleted of GSH or containing toxic levels of GSH show an intense iron starvation-like response and impairment of the activity of extramitochondrial ISC enzymes thus inhibiting oxidative endoplasmic reticulum folding, followed by death. 4.Glutathione plays an important role in preventing oxidative damage to the skin. 5.Glutathione has also been associated with skin lightening ability. 6.Glutathione utilizes different mechanisms to exert its action as a skin whitening agent at various levels of melanogenesis.