Name of drug: generic name: ampicillin sodium for injection
Ampicillin Sodium for Injection
Chinese Pinyin: Zhusheyong Anbian Xilinna
Ingredients The main ingredient of this product is ampicillin sodium, which is chemically named as (2S,5R,6R)-3, 3-dimethyl-6 - [(R) -2-amino-2-phenylacetylamino] -7-oxo-4-thiaza-1-azacyclic [3.2.0] heptane - 2-formate sodium salt.
[Properties] The product is a white or quasi-white powder or crystal.
[Indications] It is suitable for respiratory tract infection, gastrointestinal tract infection, urinary tract infection, soft tissue infection, endocarditis, meningitis, sepsis and so on caused by sensitive bacteria.
[Usage and Dosage] Adults: Intramuscular injection 2 ~ 4g a day, divided into 4 times; Intravenous infusion or injection dose is 4 to 8g a day, divided into 2 to 4 times. The daily dose can be increased to 12g for patients with severe infection, with a maximum daily dose of 14g. For children: intramuscular injection was given in 4 times per day according to body weight of 50 ~ 100mg/kg; Intravenous infusion or injection 100 ~ 200mg/kg per day according to body weight, divided into 2 ~ 4 times. The maximum daily dose is 300mg/kg according to body weight. Term newborns: 12.5-25mg /kg, once every 12 hours on the first and second day of birth, once every 8 hours on the third day to the second week, and once every 6 hours thereafter. Premature infants: 12.5 ~ 50mg/kg at the first week of birth, 1 ~ 4 weeks and above 4 weeks according to body weight.
[Adverse Reactions] Adverse reactions of this product are similar to penicillin, and allergic reactions are more common. Rash is the most common reaction, usually occurring 5 days after the administration of urticaria or maculopapules; Interstitial nephritis can also occur; Anaphylactic shock is occasionally seen. Once it occurs, emergency treatment must be carried out on the spot, with airway unblocked, oxygen inhalation, epinephrine, glucocorticoids and other treatment measures. Granulocyte and thrombocytopenia are occasionally seen in patients receiving ampicillin. Antibiotic-related enteritis is rare, with elevated serum transaminase in a few patients. Neurotoxic symptoms such as convulsions can occur after intravenous administration of large doses of ampicillin, and increased intracranial pressure may occur in infants after the administration of ampicillin, manifested as prohalogen bulge.
contraindication It is contraindicated in patients with penicillin allergy or penicillin skin test positive.
[Precautions] 1 Before applying this product, it is necessary to inquire about the history of drug allergy and conduct penicillin skin test. Patients with infectious mononucleosis, cytomegalovirus infection, lymphocytic leukemia and lymphoma are prone to skin rash when using this product, so it should be avoided. This product must be prepared fresh.
[Drug Interaction] 1 The half-life of the product will be prolonged when used in combination with promethanoxin. Ampicillin and kanamycin had synergistic antibacterial effects on Escherichia coli and Proteus. 3 this product should be separate drip, not with the following drug bottle drip: aminoglycoside drugs, clindamycin phosphate, clindamycin hydrochloride, polymyxin B, amber chloramphenicol, erythromycin, adrenaline, hydroxylamine, dopamine, atropine, calcium gluconate, vitamin B, vitamin C, amino acid nutritional injection hydrocortisone and succinic acid, etc. 4 Allopurinol may increase the incidence of ampicillin rash reactions, especially in hyperuricemia. Ampicillin can reduce the effectiveness of oral contraceptives by stimulating estrogen metabolism or reducing its hepatointestinal circulation.
[Pharmacological effects] Ampicillin sodium is a broad-spectrum semisynthetic penicillin. This product has a strong antibacterial effect on hemolytic streptococcus, streptococcus pneumoniae and non-penicillinase staphylococcus, similar to penicillin or a little less than penicillin. Ampicillin also had a good antibacterial effect on Streptococcus virifolia and was superior to penicillin in Enterococcus and Listeria. This product has antibacterial activity against Corynebacterium diphtheria, Bacillus anthracis, Actinomycetes, Haemophilus influenzae, Bortobacterium pertussis, Neisseria and anaerobic bacteria except Bacteroides fragilis. Some Proteus bizarre, Escherichia coli, Salmonella and Shigella bacteria are sensitive to this product. Ampicillin plays a bactericidal role by inhibiting bacterial cell wall synthesis.
Store in a dry place, sealed. Validity period: two years
[Specification] 2.0G (according to C16H19N3O4S)
[Approval Number] National medicine approval H20013035
FAQ 1.who are we? We are based in Fujian, China, start from 2000,sell to North America(40.00%),Southeast Asia(25.00%),Western Europe(25.00%),Africa(10.00%).There are total about50 people in our office.
2. how can we guarantee quality? Always a pre-production sample before mass production; Always final Inspection before shipment;
3.what can you buy from us? Pharmaceutical production lines,Intermediates,APIs,Finished Drug Preparations & Vaccines.
4. why should you buy from us not from other suppliers? We haveour own manufacture factories andone professional sales team working for the clients all over the world.
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Our Ddvantage: 1. Quick delivery 2. Online payment 3. Quality assurance 4. Welcome big order 5. After-sales service 24 hours 6. Competitive advantage products 7. Our value information is "Quality is our culture" 8. Work with us to provide you with secure funds, your business is securely protected, our advantages
Our Service a) Freeamples can be provided. b) Guide customers through professional technology and teach them how to use our products after sale c) Determine the lowest price of high-quality products 1.Skilledexperience: Our company is a leading manufacturer of professional production in Chinapharmaceutical field for manyyears. 2. The highest quality: to ensure high quality, once any problems are found, the package will be re-shipped for you. 3. Safe transportation: by air express (FedEx, UPS, DHL, EMS). It is recommended that you choose the most professional freightforwarder. 4. Fast delivery: We have stock, so once payment is received, we can deliver quickly. 5. Quality service: We will provide you with enthusiastic after-sales service. If you have any questions, we will reply to youwithin 24 hours. 6. Competitive price: discounts will be obtained when making large orders.
Our Manufacture Factory Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded FUL has been put into operation in many well-known pharmaceutical enterprises such as SINOPHARM, CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.
At present Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd has the SINOPHARM authorization to sell its intermediates and APIs,and has the authorizations of CSPC & HUABEI PHARM sell its finished drug preparations;then FUL is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations.