St John's Wort Extract Powder 0.3% CAS 548-04-9 Hypericin

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Product origin: Wuhan, Hubei, China

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US$ 8 ~ 100

Description

Hypericin 0.3% 548-04-9, St John's Wort Extract

Product Name:	St John's Wort Extract
Botanical Name:	Hypericum perforatum
Part Used:	Aerial parts
Active Ingredient:	Hypericin
CAS No.	548-04-9
Specification:	0.3%
Test Method:	HPLC
Appearance:	Dark Brown powder
Certificate	HALAL, KOSHER, ISO

What is St John's Wort Extract?
St John's Wort Extract was initially believed that the anti-depressant pharmacological activity of hypericin was due to inhibition of monoamine oxidase enzyme. The crude extract of Hypericum is a weak inhibitor of MAO-A and MAO-B. Isolated hypericin does not display this activity, but does have some affinity for NMDA receptors.[citation needed] This points in the direction that other constituents are responsible for the MAOI effect. The current belief is that the mechanism of antidepressant activity is due to the inhibition of reuptake of certain neurotransmitters. The large chromophore system in the molecule means that it can cause photosensitivity when ingested beyond threshold amounts.[citation needed] Photosensitivity is often seen in animals that have been allowed to graze on St. John's Wort. Because hypericin accumulates preferentially in cancerous tissues, it is also used as an indicator of cancerous cells. In addition, hypericin is under research as an agent in photodynamic therapy, whereby a biochemical is absorbed by an organism to be later activated with spectrum-specific light from specialized lamps or laser sources, for therapeutic purposes. The antibacterial and antiviral effects of hypericin are also believed to arise from its ability for photo-oxidation of cells and viral particles.

Function&Application
Function of St John's Wort Extract
St John's Wort Extract for avian influenza, atypical Newcastle disease, spread, throat, bursa of Fabricius, duck plague, duck viral hepatitis, egg drop syndrome and other viral diseases. St John's Wort Extract for poultry cold caused by high fever, difficulty breathing, cough, head and face swelling, crown purple, lack of energy, decreased intake, decreased egg production, deformed eggs more embolism. St John's Wort Extract for swine fever, blue ear disease, parvovirus, viral enteritis, infectious gastroenteritis and immune dysfunction and so on. St John's Wort Extract in vivo, in vitro are the role of retrovirus, with a strong anti-viral effect. On AIDS (HIV) early replication has a strong inhibitory effect. Can cause cancer cell programmed death, with anti-cancer effect. Can activate mononuclear phagocytic cells with enhanced immune function.

Application of St John's Wort Extract
St John's Wort Extract for mild moderate depression St John's Wort Extract for ease nerve pain,anxiety or disorders St John's Wort Extract for anti-pyretic St John's Wort Extract for cure burns & scalding

COA and other ceitificates will be sent under request.

Package	carton drum with two plastic bags inside
Net weight	25KG/Drum
Storage	Sealed in cool and dry place to avoid moisture and light
Shelf life	2 years when properly stored
Lead time	1~3 days after confirmation

Item	Specification	Result	Method
Maker Compounds	0.3% Hypericin	0.31%	HPLC
Identification	Complies by TLC	Complies	TLC
Organoleptic
Appearance	Fine Powder	Fine Powder	Visual
Color	Black-Brown	Black-Brown	Visual
Odor	Characteristic	Characteristic	Organoleptic
Taste	Characteristic	Characteristic	Organoleptic
Part Used	Whole Plant	N/A	N/A
Method of Extraction	Soak and Extraction	N/A	N/A
Extraction Solvents	Ethanol	N/A	N/A
Excipient	None	N/A	N/A
Physical Characteristics
Particle Size	NLT100%Through 80 mesh	100%	USP <786>
Loss on Drying	≤5.00%	3.45%	Draco method 1.1.1.0
Bulk Density	40-60g/100ml	54.5g/100ml	USP < 616>
Heavy metals
Residual solvent ehanol	<5000ppm	<10ppm	GC
Irradiation detection	Not irradiated(PPSL<700)	329	PPSL(CQ-MO-572)
Allergen detection	Non ETO Treated	Complies	USP
Heavy metals(as Pb)	USP standards(<10ppm)	<10ppm	USP <231>
Arsenic (As)	≤3ppm	4.32ppm	ICP-OES(CQ-MO-247)
Lead (Pb)	≤3ppm	1.02ppm	ICP-OES(CQ-MO-247)
Cadmium(Cd)	≤1ppm	1.210ppm	ICP-OES(CQ-MO-247)
Mercury(Hg)	≤0.1ppm	0.110ppm	ICP-OES(CQ-MO-247)
Pesticide Residue	Non-detected	Non-detected	USP <561>
Microbiological Tests
Total Plate Count	NMT1000cfu/g	770 cfu/g	FDA-BAM
Total Yeast & Mold	NMT100cfu/g	60cfu/g	FDA-BAM
E.Coli	Negative	Negative	FDA-BAM
Salmonella	Negative	Negative	FDA-BAM
Storage	Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.