Pharmaceutical Grade Nootropics 7, 8-Dhf Chemicals Pure 99% 7, 8-Dihydroxyflavone CAS 38183-03-8 Tropoflavin for Weight Loss and Depression

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Product origin: Wuhan, Hubei, China

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Pharmaceutical Grade Nootropics 7, 8-Dhf Raw Powder Pure 99% 7, 8-Dihydroxyflavone CAS 38183-03-8

Product name: 7,8-DIHYDROXYFLAVONE

Other Name: 7,8-Dihydroxyflavone hydrate

Appearance:Yellow Powder

CAS:38183-03-8

M.F:C15H10O4

M.W.:254.24

Specification:99%

7,8-Dihydroxyflavone (7,8-DHF) is a potent and selective TrkB receptor agonist (Kd≈320 nM). TrkB receptor is the main signal receptor of brain-derived neurotrophic factor. 7,8-Dihydroxyflavone (7,8-DHF) is a potential nootropic that may improve overall brain health, mood, and cognitive function. It may also be of benefit for several neurodegenerative and neurodevelopmental disorders, as well as obesity and elevated blood pressure.

7,8-Dihydroxyflavone is disubstituted flavone that acts as a small-molecule TrkB agonist. 7,8-Dihydroxyflavone has been shown to reverse memory deficits and BACE1 elevation in a mouse model of Alzheim er's disease. 7,8-Dihydroxyflavone may also provide a therapeutic option in the treatment of other neorological disorders such as Rett syndrome and PTSD.

7,8-Dihydroxyflavone

Other Name(s):

7,8-DIHYDROXYFLAVONE;7,8-dihydroxy-2-phenyl-4-benzopyrone;DIHYDROXYFLAVONE,7,8-(RG);7,8-Dihydroxyflavonehydrate;7,8-dihydroxy-2-Chemicalbookphenyl-1-benzopyran-4-one;8-Dihydroxyflavone;7,8-DIHYDROXYFLAVONE7,8-DIHYDROXYFLAVONE;7,8-dihydroxy-2-phenyl-4h-1-benzopyran-4-on

OVERVIEW

7,8-DHF mimics the effects of brain-derived neurotrophic factor (BDNF) in the brain by activating the tropomyosin-related kinase B (TrkB) receptors .The therapeutic potential of BDNF is restricted due to its short half-life (less than 10 minutes) and its inability to cross the blood-brain barrier because of its large size. Unlike BDNF 7,8-DHF is able to penetrate the blood-brain barrier and enter the central nervous system (CNS) .
7,8-DHF also increases the production of Nrf2. Nrf2 increases antioxidants enzymes such as heme oxygenase 1 (HO-1) and also enzymes that repair DNA (8-oxoguanine DNA glycosylase-1 - OGG1)

USES & EFFECTIVENESS
1) May Improve Memory and Learning
2) May Promote Brain Repair of damaged neurons .
3) May Be Neuroprotective
4) Has Antioxidant Effects
5) Has Anti-Inflammatory Effects(decreases the release of inflammatory factors in brain cells by blocking NF-κB )
6) May Be Beneficial in Neurodegenerative and Neurodevelopmental Diseases
7) May Treat Depression
8) May Treat Addiction
9) May Combat Obesity
10) May Improve Blood Pressure
11) May Prevent Skin Cancer( kills oral squamous cancer cells and skin cancer (melanoma) cells .)
12) May Prevent Skin Aging

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