Factory Supply Plant Extract Imperatorin 98% Powder 482-44-0 ISO Certified Reference Material 98% Imperatorin 482-44-0 Standard Reagent

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Product origin: Wuhan, Hubei, China
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US$ 10 ~ 15

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Plant extract imperatorin 98% powder 482-44-0


Product Name
Angelica dahurica Extract Imperatorin
Exterior
Brown powder(1%), write powder(98%)
Active Ingredient
Imperatorin 1% 98%
Test Method
HPLC
Extraction Solvent
Ethanol/ Water
CAS NO
482-44-0
Molecular Formula
C16H14O4
Molecular Weight
270.27996

The imperatorin extracted from the dried roots of the genus Umbelliferae has been shown to have antibacterial,
antiasthmatic,antiallergic, dilated blood vessels, and inhibition of tumor cell proliferation. Lipid microspheres and
liposomes are drug carriers prepared by using natural lipid materials such as phospholipids and cholesterol.
With this carrier, drugs can be transported to the site of the lesions, and the drug molecules can be protected
from degradation by biological enzymes. The pre-prescription study and drug stability test of imperatorin can
provide a theoretical basis for the design optimization of the injection of imperatorin microspheres. The application
of lipid microsphere technology to the study of imperatorin drugs can reduce the renal side effects of drugs under
the precursors that maintain efficacy.


Effect on the central nervous system
        The effect of imperatorin on seizures was studied using the electroconvulsive epileptic seizure
threshold model in mice. The study found that intraperitoneal injection of 50 and 100 mg/kg-1 of imperatorin
30 minutes earlier could increase the voltage threshold of seizures in mice by 38% and 68%, respectively,
and demonstrated that imperatorin improves mice with electrical stimulation. The effect of the onset threshold
is dose and time dependent.



Effects on the cardiovascular system
      The chromatographic retention peaks of imperatorin and verapamil were similar. It can reduce the protein
content and cell volume of cardiomyocytes prestimulated by angiotensin I, and its effect is dose-dependent: the
ratio of heart weight of spontaneously hypertensive rats treated with angiotensin I is significantly reduced,
indicating that the effect of angiotensin I on both in vivo and in vitro is anti-hypertrophy.



Antibacterial and antiviral activity
      Imperatorin has significant antibacterial and antiviral activity. Seven components were extracted from the
flowers of Magydaris tomcntosa, and four components, including eucrutin, were tested for bacteriostasis. It was
found that eucrutin had strong inhibitory activity against both gram-positive and gram-negative bacteria (minimum
bacteriostasis concentration was 32-128 mg-ml).

 



Medicine and Health care product

        Dahuricae dahuricae root as medicine (the main components of imperatorin, isoimperatorin), has the functions
of dispelling diseases, dehumidifying, discharging pus, promoting blood circulation and relieving pain. Cure cold,
headache, rhinitis, toothache. Red white belt, pain furuncle swelling poison and other diseases, can also be used as
spices and medicinal wine.






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2.Any inquiries will be replied within 12 hours.
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