Description
Nootropic CAS 69353-21-5 Bulk Galantamine Hydrobromide Powder
Product Description
| Product Name:Galantamine Hydrobromide
CAS:1953-04-4
MF:C17H22BrNO3
MW:368.27
EINECS:217-780-5
Mol File:1953-04-4.mol
Melting point:256 °C
alpha D20 -93.1° (c = 0.1015 in 15 ml H2O)
refractive index -95 ° (C=1.4, H2O)
storage temp. −20°C
solubility Sparingly soluble in water, very slightly soluble in anhydrous ethanol. It dissolves in dilute solutions of alkali hydroxides.
form White to off-white crystalline solid.
Water Solubility Soluble in water or DMSO |
Galantamine Hydrobromide is the hydrobromide salt form of galantamine, a tertiary alkaloid obtained synthetically or naturally from the bulbs and flowers of Narcissus and several other genera of the Amaryllidaceae family with anticholinesterase and neurocognitive-enhancing activities. Galantamine competitively and reversibly inhibits acetylcholinesterase, thereby increasing the concentration and enhancing the action of acetylcholine (Ach). In addition, galantamine is a ligand for nicotinic acetylcholine receptors, which may increase the presynaptic release of Ach and activate postsynaptic receptors.
(1) Anti-cholinesterase .
(2) Stimulate and inhibit acetylcholinesterase, regulate intracephalic nicotine receptor position.
(3) Cures the infantile paralysis sequelae, sweeny and myasthenia gravis pseudoparalytica, etc.
(4) Improve the recognition function of light, mild Alzheimer disease patients significantly, and delay the process of function decrease of brain cells.
(5) Improve the conduction between nerve and muscle.
Galantamine Hydrobromide is used for benign memory disorders to improve the patient's ability to point memory, associative learning, image recall, meaningless graphic recognition and portrait recall. It also improves memory impairment caused by dementia patients and brain organic diseases.
PRODUCT NAME |
Galantamine hydrobromide |
Storage |
Keep away from moisture and keep it sealed. |
| Items of analysis | Specification | Results |
| Description | White or off-white crystalline powder | Complies |
| Assay | 98.0-102.0% | 99.5% |
Identification | IR | Complies |
| HPLC | Complies |
| Impurity | ≤1.0% | 0.66 |
| Heavy metal | ≤10ppm | <10 |
| Burning residuet | ≤0.1% | 0.01 |
| Loss on drying | ≤0.5% | 0.27 |
| Conclusion | Conforms with enterprise standards |
Detailed Photos
Complaint
