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Factory Price Good Quality Naphazoline hydrochloride price cas 550-99-2 Raw powder 99% Purity Naphazoline hcl
| Common Name | Naphazoline hydrochloride | ||
|---|---|---|---|
| CAS Number | 550-99-2 | Molecular Weight | 246.735 |
| Density | 1.15 g/cm3 | Boiling Point | 440.5ºC at 760 mmHg |
| Molecular Formula | C14H15ClN2 | Melting Point | 254-260 °C |
| MSDS | ChineseUSA | Flash Point | 220.2ºC |
Items | Specification |
Appearance | White crystalline powder |
Identification | Meets the requirements |
Light Absorption | Meets the requirements |
Acidity or Alkalinity | Meets the requirements |
Loss on Drying | ≤1.0% |
Sulphated Ash | ≤0.1% |
Heavy Metals | ≤10ppm |
Chloride | ≤0.02% |
Assay | 98.0 ~ 100.5% |
Naphazoline (in the hydrochloride form) is the common name for 2-(1-naphthylmethyl)-2-imidazoline hydrochloride. It is a sympathomimetic agent with marked alpha adrenergic activity. It is a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane. It acts on alpha-receptors in the arterioles of the conjunctiva to produce constriction, resulting in decreased congestion. It is an active ingredient in several over-the-counter formulations including Eucool, Clear Eyes and Naphcon eye drops.
1.Hypersensitivity to naphazoline
2.Patients taking MAO inhibitors can experience a severe hypertensive crisis if given a sympathomimetic drug such as naphazoline HCl
3.Use in infants and children can result in central nervous system depression, leading to coma and marked reduction in body temperature
4.Should be used with caution in patients with severe cardiovascular disease including cardiac arrhythmia and in patients with diabetes, especially those with a tendency toward diabetic ketoacidosis
5.Drug interactions can occur with anaesthetics that sensitize the myocardium to sympathomimetics (e.g. cyclopropa or halothane cautiously)
6.Exercise caution when applying prior to use of phenylephrine.
7.Extended use may cause rhinitis medicamentosa, a condition of rebound nasal congestion.
Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
