Complaint
| Product name:Agomelatine Powder |
| Other Name: 2-(2-oxopyrrolidin-1-yl)butanamide |
| Appearance:White Powder |
| CAS:138112-76-2 |
| M.F.:C15H17NO2 |
| M.W.:243.3 |
| Specification:99% |
Agomelatine is a melatonergic antidepressant developed by the pharmaceutical company Servier. It is marketed for the treatment of major depressive disorder and has been reported to not produce discontinuation syndrome and have no sexual side effects compared to SSRIs, SNRIs and the older tricyclic antidepressants. Agomelatine may also have positive effects on sleep..
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| ITEM | SPECIFICATION | RESULT | METHOD |
| Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
| Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
| Specific Optical | -2.4°~ -2.8° | -2.72° | |
| Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
| Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
| Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
| Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
| Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
| pH | 4.5~7.0 | 5.10 | |
| Related substance | Spot not bigger than standard solution spot | No spot | TLC |
| Water Content | ≤2% | 0.26% | KF |
| Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
| Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
1.As a Pharmaceutical Intermediates, Agomelatine is used in the treatment of major depressive disorder, emotional disorder.
2.Agomelatine is used in the treatment of major depressive disorder, emotional disorder. The drug substance for Nervous system. Antidepressant, anxiolytic, adjusting the rhythm of sleep and regulating biological clock.
Application:
![CAS 138112-76-2 Agomelatine / Melitor / Valdoxan / Melitor / Thymanax / Agomelatin / N-[2- (7-Methoxynaphth-1-yl) Ethyl]Acetamide](https://img.china-sups.com/45aceb5cd536d8f8bd185bb2e321d517.jpg)
