Complaint
Ribosome subunits bind, interfering with the bacterial tRNA/mRNA interaction, and ultimately inhibiting the bacterial protein synthesis and antibacterial effect. Recent studies have shown that doxycycline also has many non-antibiotic biological effects.
It can partially protect MTECl(thymic medullary type epithelial cell line1) against mmc-induced apoptosis and promote the proliferation of mouse thymic epithelial cell line (MTEC1) through MAPK pathway. Meanwhile, it can also promote the secretion of il-6 and gm-csf through nf-kappab and MAPK pathways.
And thymic epithelial cells can promote the development and differentiation of thymic cells. Therefore, doxycycline plays a role in promoting the repair and reconstruction of cellular immune system damage caused by diseases in clinical treatment. Therefore, doxycycline not only has broad-spectrum antibacterial and anti-mycoplasma effects, but also has non-antibiotic immune-enhancing effects.
