Complaint
| Product Name | Pharmaceutical Milrinone Lactate Powder CAS 100286-97-3 Milrinone Lactate API for Cardiotonic |
| CAS | 100286-97-3 |
| Appearance | White powder |
| Molecular formula | C15H15N3O4 |
| Molecular Weight | 301.3 |
| Assay | 98% |
| Shelf Life | 24 months when properly stored |
| Storage | Keep in a cool, dry, dark location |
What is Milrinone Lactate ?Milrinone, is a medication used in patients who have heart failure. It is a phosphodiesterase 3 inhibitor that works to increase the heart's contractility and decrease pulmonary vascular resistance. Milrinone also works to vasodilate which helps alleviate increased pressures (afterload) on the heart, thus improving its pumping action. While it has been used in people with heart failure for many years, recent studies suggest that milrinone may exhibit some negative side effects that have caused some debate about its use clinically. |
Overall, milrinone supports ventricular functioning of the heart by decreasing the degradation of cAMP and
thus increasing phosphorylation levels of many components in the heart that contribute to contractility and
heart rate. Milrinone use following cardiac surgery has been under some debate because of the potential
increase risk of postoperative atrial arrhythmias. However, in the short term milrinone has been deemed
beneficial to those experiencing heart failure and an effective therapy to maintain heart function following
cardiac surgeries. There is no evidence of any long term beneficial effects on survival.
