Complaint
Name: Clarithromycin
English synonyms: 6-O-Methylerythromycin,A-56268,TE-031,Biaxin
CAS Number: 81103-11-9
Molecular formula: C38H69NO13
Molecular weight: 747.95
EINECS number: 1806241-263-5
Melting point: 217-220°C
Specific optical rotation: D24-90.4°(c=1inCHCl3)
Boiling point: 86°C
Density: 1.1334(rough estimate)
Refractive index: -92°(C=1,CHCl3)
Flash point: >110°(230°F)
Storage conditions: -20°C
Solubility: Soluble in DMSO
Acidity coefficient (pKa):
pKa8.99(H2Ot=25.0I=0.167)(Uncertain)
Form: powder
Color: colorless to faint yellow
Water solubility: 99.48mg/L (20ºC)
Stability: Store in Freezer
Clarithromycin is a semi-synthetic macrolide antibiotic, which can inhibit bacterial protein synthesis and achieve antibacterial effect. It can exert a strong antibacterial effect against gram-positive bacteria and gram-negative bacteria, and can significantly improve the clinical symptoms of patients . It has a wide range of clinical applications, including soft tissue infections, skin infections, respiratory and urinary system infections, and the treatment of Helicobacter pylori eradication.
