API Nootropics Idebenone CAS 58186-27-9 Raw Material

API Nootropics Idebenone CAS 58186-27-9 Raw Material

Idebenone (trade names Catena, Raxone, Sovrima, among others) is a drug that was initially developed by Takeda Pharmaceutical Company for the treatment of Alzheimer's disease and other cognitive defects. This has been met with limited success. The Swiss company Santhera Pharmaceuticals has started to investigate it for the treatment of neuromuscular diseases. In 2010, early clinical trials for the treatment of Friedreich's ataxia and Duchenne muscular dystrophy have been completed. As of December 2013[update] the drug is not approved for these indications in North America or Europe, but it is approved for the treatment of Leber's hereditary optic neuropathy (LHON) in Europe. Chemically, idebenone is an organic compound of the quinone family. It is also promoted commercially as a synthetic analog of coenzyme Q10 (CoQ10).
1.Idebenone increases nerve growth (NGF) in the brain.
2.Idebenone is a powerful antioxidant and positively affects brain chemistry.
3.Idebenone has been shown to promote information transfer across the corpus callosum, the membrane separating the right and left brain hemispheres. 
4. Idebenone has been used to treat Alzheimer's and to lessen damage from strokes.
5. Idebenone can increase production of the brain neurotransmitters serotonin, dopamine, adrenalin, and noradrenanlin.

1. Pharmaceutical
Improve brain function metabolism and brain dysfunction, can improve the utilization of glucose in the brain, and promote ATP generation;
Can improve brain neurotransmitter 5-HT metabolism, with strong antioxidant and scavenging free radicals.
Mainly used in the clinical treatment of oxidative stress-related central nervous system degenerative diseases such as Parkinson's disease, Alzheimer's disease, multi-infarct dementia, cerebral anemia and cerebral failure, also used in Friedreich Ataxia treatment.
2.Cosmetics
Used in cosmetic formulations, with the functions of scavenging free radicals, inhibiting lipid peroxidation, inhibiting inflammation, inhibiting DNA damage, protecting light and reducing pigmentation.