Bromhexine hydrochloride Product Name Bromhexine hydrochloride
CAS 611-75-6
MF C14H21Br2ClN2
MW 412.59
EINECS 210-280-8
MOL File 611-75-6.mol
Chemical Properties
Melting point 240-244 °C storage temp. Sealed in dry,Room Temperature solubility Very slightly soluble in water, slightly soluble in alcohol and in methylene chloridee. form powder λmax 307nm(Decane)(lit.) Merck 14,1391 BRN 4848376 InChIKey UCDKONUHZNTQPY-UHFFFAOYSA-N CAS DataBase Reference 611-75-6(CAS DataBase Reference)
Usage And Synthesis Description
Bromhexine Hydrochloride is the hydrochloride salt form of bromhexine, a secretolytic, with mucolytic activity. Upon administration, bromhexine increases lysosomal activity and enhances hydrolysis of acid mucopolysaccharide polymers in the respiratory tract. This increases the production of serous mucus in the respiratory tract, which makes the phlegm thinner and decreases mucus viscosity. This contributes to its secretomotoric effect, and allows the cilia to more easily transport the phlegm out of the lungs. This clears mucus from the respiratory tract and may aid in the treatment of respiratory disorders associated with abnormal viscid mucus, excessive mucus secretion and impaired mucus transport.
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