Complaint
| Product name: Lidocaine Hydrochloride |
| Other Name: Lidocaine HCl |
| Appearance:White Powder |
| CAS:73-78-9 |
| M.F:C14H23ClN2O |
| M.W.:270.8 |
| Specification:99% |
Lidocaine is a local anesthetic and antiarrhythmic drug. It is a derivative of but does not have the hallucinogenic and addictive components of.The hydrochloride of lidocaine is a white crystalline powder, easily soluble in water, and its toxicity is comparable to that of procaine, but the local anesthetic effect is strong and lasting, and it has good surface penetration. It can be injected or used for surface anesthesia.Lidocaine is a very good local anesthetic, which usually takes effect one to three minutes after application and lasts one to three hours.
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| ITEM | SPECIFICATION | RESULT | METHOD |
| Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
| Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
| Specific Optical | -2.4°~ -2.8° | -2.72° | |
| Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
| Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
| Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
| Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
| Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
| pH | 4.5~7.0 | 5.10 | |
| Related substance | Spot not bigger than standard solution spot | No spot | TLC |
| Water Content | ≤2% | 0.26% | KF |
| Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
| Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
