Complaint
GMP Factory Supply Good Quality DMPS Raw powder high Purity 99% DMPS
DMPS is the organosulfur compound with the formula C3H9NaO4S3. This colorless solid contains two carboxylic acid and two thiol groups, the latter being responsible for its mildly unpleasant odour. It occurs in two diastereomers, meso and the chiral dl forms. The meso isomer is used as achelating agent. The acid is most often used as a treatment for heavy metal toxicity, and is a water soluble and non-toxic substance.| Name | DMPS |
| Purity: | 98%min |
| Grade : | Medicine Grade |
| Appearance: | White or off-white crystalline powder |
| Assay: | 98%min |
TEM | SPECIFICATION | METHOD REFERENCE |
Appearance | white powder | Visual |
Ammonium | ≤200ppm | USPmonograph |
Chloride | ≤200ppm | USP35<221> |
Sulfate | ≤300ppm | USP35<221> |
Iron | ≤10ppm | USP35<241> |
Arsenic | ≤2ppm | USP35<211> |
Heavy metals | ≤10ppm | USP35<231>Method I |
Loss on drying(3h at 105 ºC) | ≤0.5% | USP35<731> |
Residue on Ignition | ≤0.1% | USP35<281> |
Total impurities | ≤2.0% | USP monograph |
Assay(dry basis) | 98.0% to 101.0% | USP monograph |
Function
DMPS is indicated for the treatment of lead poisoning in children with blood level measured above 45 µg/dL. The use of DMPS is not approved for prophylactic/prevention of lead poisoning in anticipation of exposure in known lead contaminated environments. Its elimination half-life is 2.5-3.5 h. DMPS can cross the blood-brain barrier of mice, but not that of humans, limiting its use to extracting heavy metals from parts of the body other than the central nervous system.
Another application for DMPS is for provocation of tissue heavy metals in anticipation of a urine test. This is sometimes called a "challenge" or "provoked" heavy metals test. DMPS is used to help mobilize heavy metals stored in body tissues (and therefore not typically present in the circulation) and increase the excretion of heavy metals in the urine. In a study by Howard Frumkin et al., this sort of test was shown to not reliably provide an indication of past chronic mercry exposure, something it was often used for. A 2004 study by GP Archbold, et al. called the results of a DMPS challenge test "misleading" for the purposes of diagnosing mercry toxicity. Moreover, DMPS share the limitation of extracellular distribution, which makes it unable to cross the cell membrane and chelate heavy metals from intracellular sites.
The relative activities of a series of novel monoalkyl esters of 2,3-dimercapto-1-propanesulfonate Sodium (DMPS) have been examined as agents for the mobilization of cadmum, lead and arsenic owing to the ability of these monoesters to cross cell membranes. The monoesters were found to be more effective than the parent compound DMPS.
Application
| Product Name | CAS No. | Product Name | CAS No. |
| Lufenuron | 103055-07-8 | Toltrazuril | 69004-03-1 |
| Nitenpyram | 120738-89-8 | Praziquantel/Biltricide | 55268-74-1 |
| Fenbendazole | 43210-67-9 | Tetramisole Hcl | 5086-74-8 |
| Levamisole | 14769-73-4 | Ponazuril | 9004-4-2 |
| Diclazuril | 101831-37-2 | Florfenicol | 73231-34-2 |
| Ivermectin | 70288-86-7 | Enrofloxacin Hcl | 112732-17-9 |
| Albendazole | 54965-21-8 | Mebendazole | 31431-39-7 |
Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
