Complaint
| D-Proline Chemical Properties |
| Melting point | 223 °C (dec.) (lit.) |
| alpha | 84.75 º (c=4, H2O) |
| Boiling point | 215.41°C (rough estimate) |
| density | 1.36 |
| refractive index | 85 ° (C=4, H2O) |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 1.952(at 25ºC) |
| form | Powder |
| color | White to yellow to pale brown |
| optical activity | [α]22/D +85.0°, c = 4 in H2O |
| Water Solubility | soluble >1000 g/L (20 ºC) |
| Sensitive | Hygroscopic |
| BRN | 80811 |
| InChIKey | ONIBWKKTOPOVIA-SCSAIBSYSA-N |
| CAS DataBase Reference | 344-25-2(CAS DataBase Reference) |
| EPA Substance Registry System | D-Proline (344-25-2) |
| Safety Information |
| Hazard Codes | Xi,Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 22-24/25-36/37/39-26 |
| WGK Germany | 3 |
| F | 3-10 |
| Hazard Note | Irritant |
| TSCA | Yes |
| HS Code | 29339990 |
| D-Proline Usage And Synthesis |
| Chemical Properties | White to off-white powder |
| Uses | Used in the synthesis of (R)-(+)-N-Boc-Pipecolic Acid, (S)-(-)-Coniine, (S)-(+)-Pelletierine, (+)-.beta.-Conhydrine, and (S)-(-)-Ropivacaine and forma l synthesis of (-)-Lasubine II and (+)-Cermizine C. |
| Uses | Labelled D-Proline Lasubine II and (+)-Cermizine C. |
| Uses | proline is a skin-conditioning agent. An amino acid found in the collagen molecule. |
| Definition | ChEBI: The D-enantiomer of proline. |
| Synthesis Reference(s) | Journal of the American Chemical Society, 71, p. 2818, 1949 DOI: 10.1021/ja01176a065 Tetrahedron Letters, 28, p. 6469, 1987 DOI: 10.1016/S0040-4039(00)96890-4 |
