Rotundine powder, an analgesic drug, has been entrapped in a PIC polysaccharide granule. It was prepared in a two-step process, i.e., first granulation of a chitosan acetated solution containing Rotundine and then complexation of the polycationic component on the granular surface with a polyanionic solution of carboxymethyl glucomannan (CMGM). The granule has an average diameter of 1.38-1.53 mm and the drug content reaches 62.8%.
Product Name | Rotundine |
CAS | 10097-84-4 |
Appearance | White crystalline powder |
MF | C21H25NO4 |
Molecular Weight | 355.43 |
Purity | 99% |
Storage | Keep in a cool, dry, dark location in a tightly sealed container or cylinder |
Shelf Life | 24 Months |
ITEMS OF TEST | STANDARD | RESULTS OF ANALYSIS |
Appearance | White to almost white crystalline powder | White crystalline powder |
Identification | A: Infrared absorption B: Ultraviolet absorption C: Thin-layer chromatographic identification | Conforms Conforms Conforms |
Loss of drying | NMT 0.50% | 0.31% |
Melting range | 136 -142°C | Confirms |
Heavy metals | NMT 20ppm | <20ppm |
Residue on ignition | NMT 0.10% | 0.05% |
3-Amino-1-propanol | NMT 0.50% | 0.18% |
Aceton | NMT 0.020% | Negative |
Isopropyl alcoho | NMT 0.20% | Negative |
Chromatographic purity | Total impurities: NMT1.00%Single impurity: NMT0.50% | Conforms Conforms |
Assay | Not less than 98.00% and not more than 102.00% | 99.64% |
1.Nourishing and strengthening kidney function;
2.Protecting the liver from the damage of chemical poisons, preventing the damage of oxygen free radical;
3.Enhancing human immunity and resisting the diseases;
4.Enhancing intelligence and promoting physical endurance.
Name | CAS No. | Purity |
Sunifiram | 314728-85-3 | 99.0% |
Unifiram | 272786-64-8 | 99.0% |
Idebenone | 58186-27-9 | 99.0% |
Pramiracetam | 68497-62-1 | 99.0% |
Fasoracetam | 110958-19-5 | 99.0% |
Oxiracetam | 62613-82-5 | 99.0% |
Phenylpiracetam hydrazide | 77472-71-0 | 99.0% |
Galantamine Hydrobromide | 69353-21-5 | 98.0% |
Tianeptine | 66981-73-5 | 99.0% |
Tianeptine sodium | 30123-17-2 | 99.0% |
Tianeptine hemisulfate monohydrate (THM) | 1224690-84-9 | 99.0% |
9-ME-BC(9-Methyl-9H-beta-carboline) | 2521/7/5 | 99.0% |
Agomelatine | 138112-76-2 | 99.0% |
6-Paradol 98% | 27113-22-0 | 98% Oil form |
6-Paradol 50% | 27113-22-0 | 50% Powder form |
Nicotinamide Riboside Chloride(NRC) | 23111-00-4 | 98.0% |
Beta-Nicotinamide Mononucleotide(NMN) | 1094-61-7 | 99.0% |
β-Nicotinamide Adenine Dinucleotide(NAD+) | 53-84-9 | 98.0% |
Noopept,GVS-111 | 157115-85-0 | 99.0% |
Piracetam | 7491-74-9 | 99.0% |
Phenibut | 1078-21-3 | 99.0% |
Coluracetam | 135463-81-9 | 99.0% |
N-Methyl-D-aspartic acid(NMDA) | 6384-92-5 | 99.0% |
Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 99% Powder form |
Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 50% Graininess form |
Citicoline | 987-78-0 | 99.0% |
PRL-8-53 | 51352-87-5 | 98.0% |
NSI-189 Phosphate | 1270138-41-4 | 99.0% |