High Quality Alendronate Sodium CAS 121268-17-5 For Anti-osteoporosis
Product Name: Alendronate sodium
Synonyms: G-704650;Fosamsx;4-amino-1-hydroxy-1-phosphonobutyl phosphonic acid, monosodium, MK-217;Alendronate trihydrate sodium;P,P'-(4-Amino-1-hydroxybutylidene)bis-phosphonicacidmonosodiumsalt;Alendronate Sodium (200 mg);SodiuM Alendronate, EP;MonosodiuM Alendronate Trihydrate
CAS: 121268-17-5
MF: C4H12NO7P2.Na.3H2O
MW: 325.12
EINECS: 601-766-4
Product Categories: Miscellaneous Biochemicals;REQUIP;Osteoporosis;Inhibitors;Miscellaneous Compounds;Phosphorylating and Phosphitylating Agents;All Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 121268-17-5.mol
Alendronate sodium trihydrate is used as a bone resorption inhibitor, farnesyl diphosphate synthase inhibitor and CD45 protein tyrosine phosphatase inhibitor. A robust inhibitor of bone resorption that induces apoptosis. Alendronate inhibits the migration and invasion of PC-3 cells (sc-2220) by interfering with the mevalonate pathway. Additionally, Alendronate, Sodium Salt is an inhibitor of CD45RC and MMP.
Alendronate Sodium CAS 121268-17-5 of Chemical Properties
Melting point 245°C
storage temp. -20°C
solubility water, double-distilled: 10 mg/mL
form solid
color white
Water Solubility Soluble in water at 10mg/ml
Merck 14,229
Stability: Store in freezer
InChIKey NKENDYHBVCKCNL-UHFFFAOYSA-M
CAS DataBase Reference 121268-17-5(CAS DataBase Reference)
Function and Application of Alendronate Sodium CAS 121268-17-5
1. Alendronate sodium trihydrate is used as a bone resorption inhibitor, farnesyl diphosphate synthase inhibitor and CD45 protein tyrosine phosphatase inhibitor. A robust inhibitor of bone resorption that induces apoptosis. Alendronate inhibits the migration and invasion of PC-3 cells (sc-2220) by interfering with the mevalonate pathway. Additionally, Alendronate, Sodium Salt is an inhibitor of CD45RC and MMP.
2. Alendronate sodium is a bisphosphonate used as a bone reabsoption inhibitor
3. Alendronate sodium is a dopamine receptor agonist, antiParkinsonian
4. Alendronate sodium Inhibits bone resorption and increases bone density.
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