World Well-Being Biotech ISO&FDA Certified 10%-98% Polysaccharides 1%-98% Astragaloside IV CAS 83207-58-3 98% Cycloastrogenol CAS 78574-94-4 Astragalus Extract

Min.Order: 1
Product origin: Changde, Hunan, China
Infringement complaint: complaintComplaint
US$ 10 ~ 50

Description
Product Description
Product NameAstragalus Extract 
Botanical NameAstragalus propinquus
Part UsedRoot
AppearanceBrownish Yellow to White powder
Specification4:1 10:1
Straight Powder
10%-98% Polysaccharides
1%-20% 50% 70% 90% 98% Astragaloside IV 
98% Cycloastrogenol 
Storage Period24 Months
Package1kg/bag 25kg/drum
Storage ConditionsStore in cool and dry places. Keep away from strong light and heat.

Description
Astragalus is an herbaceous perennial plant that grows about 16 to 36 inches (three feet) tall. It grows well in grassy regions and on mountainsides, requiring plenty of exposure to the sun. The plant prefers sandy, well-drained, well loosened soil and free of stones or debris. Sandy soil is ideal because it allows good root growth. Root is cylindrical, not usually branched, 30 -90 cm long, and covered with a tough, yellowish-brown skin with a sweet white inner pulp. Its roots are used in traditional Chinese Medicine, in which it's been used as an adaptogen for thousands of years, meaning it helps the body fight off stress and disease. The plant has short vertical or raised, hairy stems.

Leaves & fruit
Leaves made up of 12 to 18 pairs of leaflets. Leaflet blade is wide oval or elliptical, and pubescent below. Stipules are lanceolate. Racemes are axillary. The plant has a dense brush of white or yellow flowers in the appearance reminiscent of peas. Flowering normally occurs from June to July. Fruit is oval or egg-shaped beans. Seeds are small and kidney shaped. Roots are used in traditional Chinese Medicine, in which it's been used as an adaptogen for thousands of years. The roots are traditionally harvested when the plant is between 4-5 years old and sliced when fresh into long thin strips that look like tongue depressors.  The root has sweet, warming taste.

Health Benefits
Known as Astragalus Propinquus scientifically, the roots of this herb are known to heal different health conditions. Thanks to its healing properties, including antiviral, antibacterial, adaptogenic, anti-hydrotic, anti-inflammatory, antioxidative, anti-hypertensive, and anti-cancerous properties, the herb is an essential part of several alternative branches of medicine. Listed below are few of the health benefits of Astragalus

1. Helps Maintain Cholesterol Levels
Regular intake of astragalus roots is known to reduce bad cholesterol in the blood. Roots curb the absorption of fat from intestines, plus it also acts as a natural detoxification agent. It maintains your arterial walls from the deposits of plaques and shields you from many conditions, including atherosclerosis.

2. Prevent Diabetes
Astragalus could effectively control blood glucose, reduce the free radicals, and encourage the antioxidative activity and may play a role in the treatment of gestational diabetes in pregnant women. It helps to reduce insuli resistance and ER stress induced by high glucose in animals.

Astragalus improved fasting blood glucose levels, glomerular filtration rate (GFR), urinary albumin rate and thickness of the glomerular basement membrane in diabetic rat models. It can increase pancreatic beta cell mass in type 1 diabetic mice strongly associated with an improved autoimmunity.(1), (2), (3), (4)

3. Prevent Respiratory Problems
Astragalus played an important role in preventing the recurrence of asthma in children. A combination of astragalus and hormones showed better effects.

Astragalus could prevent the development of chronic asthma, therefore reducing asthma attacks in an ovalbumin sensitized mouse model exposed to repeated Ovalbumin. It may reduce the incidence of Upper Respiratory Tract Infection (URTI) in children with nephrotic syndrome.(5),(6), (7)

4. Prevents Memory Loss
Astragalus helps to enhance the functional recovery in intracerebral hemorrhagic stroke patients. Astragalus injection is an effective drug for the treatment of elderly patients with chronic primary insomnia and has fewer side effects.

Astragalus extract improves nerve injury after brain restriction of blood (ischemia) in mice. Astragalus could be used for curing Parkinson's disease; it decreased the levels of dopamines in 6-hydroxydopamine induced substantia neuron cells. Extract of Astragalus had protective effects on DEX (dexamethason)-induced neuron injury mouse model. Active components of Astragalus reduced iron overload in Alzheimer's disease brain model of rat.(8), (9), (10), (11), (12), (13)

5. Reduces Fatigue
Astragalus helps to reduce fatigue by increasing the oxygen uptake and the systemic utility of oxygen in athletes. It can significantly reduce the exercise induced physical fatigue of altitude induced low oxygen mice and improved exercise performance in trained mice. Astragalus flavonoids decrease chronic fatigue syndrome induced by food intake restriction plus forced swimming in rats.(14), (15), (16), (17)

6. Combats Stress
High anxiety and chronic stress can be very dangerous, as stress hormones can cause havoc on a healthy system when not kept in check. Thus, finding ways to relax is essential, and astragalus has been credited to reduced stress levels and a general promotion of peace and calm. For those suffering from mood swings and constant nervous tension, astragalus can rebalance your hormonal levels.(18), (19)

7. Protects the Liver
Oral administration of alcoholic extract of Astragalus root reduced the liver injury induced by stilbenemidine. Consumption of Traditional Chinese Medicine may be useful in preventing and improving fatty liver induced by alcohol.(20), (21)

8. Anti-Aging
Everyone wants to "live forever". There has been a great deal of research done on the effects of astragalus and its antioxidant potential. It can considerably help to decrease signs of aging on the face, promote regrowth of tissue, remove free radicals, and prevent or reverse chronic illness symptoms. More and more people are turning to astragalus for its obvious anti-aging effects. This is particularly accurate for the skin, and for blemishes, wrinkles, and age spots, astragalus extract can be a powerful remedy.(22)

9. Improve Male Fertility
Astragalus revealed a significant stimulatory effect and increased the motility of human sperms in lab. Astragalus has beneficial effects and is able to improve relative testes weight, sperm parameters and cAMP-responsive element modulator (CREM) expression against CP-induced reproductive toxicity in male mice.

Astragalus could significantly reduce the apoptosis of spermatogenic cells, decrease the level of fat peroxidation and protect glutathione activity in the torsional testis.(23), (24)

10. Helps Bone Function
Astragalus extracts considerably improved bone mineral density, biochemical density and ash weight of the femur and tibia in rats with their ovaries taken out. When combined with supplemental calcium it could also be more protective against the calcium loss in calcium-insufficient postmenopausal women.(25)

11. Prevents the Growth of Tumors
Research has shown the success of astragalus saponins, flavonoids and polysaccharides in decreasing or eliminating tumors. In cases of chemoresistance treating liver cancer, astragalus has shown potential in reversing multidrug resistance and as an addition to conventional chemotherapy, according to a research published in the Journal of Pharmacy and Pharmacology.(26)

12. Effective in Wound Healing
Topical application of Astragalus has useful effects in the acceleration of skin wound contraction and healing. Astragalus decreased Catenin beta-1 to increase skin cell migration and propagation; hence it could promote ulcerated wound healing in cultured mouse keratinocytes.

Astragalus has shown to be a promising natural product with both healing and anti-scar effects for wound treatment. These findings suggest the use of Astragalus in the treatment of injury.(27), (28), (29), (30)

13. Allergy Relief
Millions of people suffer through seasonal allergies during fall and spring. Astragalus root extract has shown great potential in reducing the severity of allergic reactions. Although the chemical pathway isn't completely understood, it is supposed that the chemical components in astragalus help to prevent the release of histamines, which cause the allergic reactions, such as runny noses, itchy eyes, and other irritating symptoms.(31)

14. Protect the Intestine
Astragalus helps to strengthen the movement and muscle tonus in the intestine. High dose of Astragalus has a protective effect on hemorrhagic shock-reperfusion injury of the intestinal mucosa. Astragalus Polysaccharide effectively reduces TNBS induced experimental colitis in rats.(32),(33),(34)

15. Treats Colds and Flu
Astragalus has antiviral capabilities so it has long been used to treat common colds and the flu. It's commonly combined with other herbs like ginseng, angelica and licorice. As with many other natural cold remedies, it seems to work better when used when healthy individuals use the supplement regularly in order to prevent the illness before it happens. Regular use of astragalus before the colder months of winter is said to prevent or decrease the number of colds and upper respiratory illnesses individuals will have throughout the season.(35)

16. Reduces Sleep Issues
Insomnia, sleeplessness, interrupted sleep patterns can be cured by regular consumption of astragalus root. By improving overall health, metabolism and hormonal balance this root can help in delivering a peaceful sleep.
 
Physical Control
Appearance Fine PowderCompliesVisual
ColorLight Yellow PowderCompliesVisual
Odor CharacteristicCompliesOrganoleptic
Taste CharacteristicCompliesOrganoleptic
Particle Size 95100% pass 80 meshComplies80 Mesh Screen
Loss on Drying  5% Max4.34%CPh
Ash5%Max3.75%CPh
Part of Plant UsedRootComplies/
Solvent Used Water & EthanolComplies 
Excipient5%-10% MaltodextrinComplies 
Chemical Control
Heavy metals NMT 10 ppmConformsAtomic Absorption
Arsenic (As)NMT 2ppmConformsAtomic Absorption
Mercury(Hg)NMT 1ppmConformsAtomic Absorption
Lead (Pb)NMT 2ppmConformsAtomic Absorption
GMO StatusGMO FreeConforms/
Solvent Residual Meet E.P StandardConformsPh.Eur
Pesticides Residues Meet USP StandardConformsGas Chromatography
Benzo(a)pyreneNMT 10ppbConformsGC-MS
Sum of benzo(a)pyrene, benz(a)anthracene, benzo(b)fluoranthene and chryseneNMT 50ppbConformsGC-MS
Microbiological Control
Total Plate Count  10000cfu/g MaxConformsAOAC
Yeast & Mold 300cfu/g MaxConformsAOAC
S. aureusNegativeNegativeAOAC
E.Coli Negative NegativeAOAC
Salmonella NegativeNegativeAOAC
Pseudomonas aeruginosaNegativeNegativeUSP
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