Cryptococcal Capsular Polysaccharide Detection K-Set (Lateral Flow Assay)

Product Introduction

FungiXpert® Cryptococcal Capsular Polysaccharide Detection K-Set (Lateral Flow Assay) is used for qualitative or semi quantitative detection of cryptococcal capsular polysaccharide antigen in serum or CSF, the K-Set is mainly used in the clinical diagnosis of cryptococcal infection.

Cryptococcosis is an invasive fungal infection caused by the Cryptococcus species complex (Cryptococcus neoformans and Cryptococcus gattii). Individuals with impaired cell-mediated immunity are at greatest risk of infection. Cryptococcosis is one of the most common opportunistic infections in AIDS patients. Detection of cryptococcal antigen (CrAg) in human serum and CSF has been extensively utilized with very high sensitivity and specificity.

Characteristics

Advantage

• Rapid and multi-choice
  Obtain result within 10 min
• Qualitative / Semi-quantitative / Quantitative results available
• Simple
  Easy to use, ordinary laboratory staff can operate without training
• Intuitive, visual reading result

• Intuitive, visual reading result
• Accurate
  Low detection limit: 0.5ng/mL
  Sensitivity & Specificity: > 99% for both sample type
• Economical
  Product can be transported and stored at room temperature, reducing costs

• Methodology comparison
  Adapted from Kozel and Bauman, Expert Opin. Med. Diagn. (2012) 6:245

Operation

Qualitative procedure

 Semi-quantitative procedure

 For quantitative test