Ganirelix is a synthetic decapeptide compound. Its acetate, Ganirelix Acetate, is a releasing hor mone (Gn RH) receptor antagonist. The amino acid sequence is: Ac-D-2Nal-D-4Cpa-D-3Pal-Ser-Tyr-D-Ho ChemicalbookmoArg(9,10-Et2)-Leu-L-HomoArg(9,10-Et2)-Pro-D- Ala-NH2. Clinically, it is mainly used in women receiving assisted reproductive technology in controlled ovarian stimulation programs to prevent premature lutei nizing hormone peaks and to treat fertility disorders caused by this reason.
Application:
It is primarily used in assisted reproduction to control ovulation. The drug works by blocking the action of Gn RH upon the pituitary, thus rapidly suppressing the production and action of L H and F SH.