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Lidocaine HCL details | Chemical Name | Lidocaine hydrochloride |
| Synonyms | LIDOCAINE HCL;2-(diethylamino)-N-(2,6-dimethylphenyl)acetamide,hydrochloride;Xilina hydrochloride;Lidothesin;Xyloneural;Expand |
| CAS No. | 73-78-9 |
| Molecular Formula | C14H23ClN2O |
| Molecular Weight | 270.79800 |
| PSA | 32.34000 |
| LogP | 3.45870 |
What is Lidocaine hydrochloride ?
- Lidocaine hydrochloride,2-(diethylamino)-2 ,6 -acetoxylidide monohydrochloride(Xylocaine), was conceived as a derivative of gramine(3-dimethylaminomethylindole) and introduced as a localanesthetic. It is now being used intravenously as a standardparenteral agent for suppression of arrhythmias associatedwith acute myocardial infarction and cardiac surgery. It isthe drug of choice for the parenteral treatment of prematureventricular contractions.
Application:
Lidocaine hydrochloride is characterized by strong penetration, strong dispersion, rapidly onset. The anesthetic performance is twice that of procaine and the toxicity is1. There is an anesthetic effect after 5 minutes treatments, and anesthesia can last 1 to 1.5 hours, 50% longer than procaine. The drug is effective on the heart of the disease or arrhythmia caused by cardiac glycoside, but on the supraventricular tachycardia is poor. This product is fast and oral ineffective, with short duration, and often used as intravenous administration.
Usage and dosage:
Surface anesthesia with solution of 2% to 5%.Infiltration anesthesia with solution of 0.25% to 0.5%, conduction anesthesia with 2%, each injection point, horse, cattle 8 to 12 ml, sheep 3 to 4 ml. Epidural anesthesia with 2% solution, horse, cow, 8 to 12 ml, dog, cat, 0.22 ml per kilogram of body weight. Subcutaneous injection with 2% solution, pig, sheep, 80 ml, horse, cow, 400 ml, dog,25 ml, cat, 8.5 ml.
Treatment of arrhythmia, intravenous injection: Per kg of dog's body weight of the initial dose is 2 to 4 mg, followed by 25 to 75 micrograms per minute intravenous infusion; Cat initial dose of 250 to 500 micrograms, followed by intravenous infusion of 20 micrograms per minute.
What is the difference between the anesthetic intensity of tetracaine hydrochloride powder and lidocaine, procaine and Dimetho?
- Role: local anesthetics. Tetracaine base >tetracaine hcl>lidocaine>lidcaine hcl> benzocaine > procaine>procaine hcl, but the corresponding side effects will also increase.
- It's not that the greater the intensity of anesthesia, the better, unless you want to suffer from more side effects. Generally choose the one that suits you.
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