Antibiotic Medicine Amoxicillin and Clavulanate Potassium Tablet 875mg+125mg Shinepharm

Min.Order: 50,000
Product origin: Hefei, Anhui, China
Infringement complaint: complaintComplaint
US$ 0.65 ~ 0.96

Description

Composition:
Amoxiciln and Clavulanate Potassium 1g Film Coated Tablet: Each film coated tablet contacines Amoxiilin Trihydrate USP equivalent to Amoicilin 875mg and Clavulanate Potassium USP equivalent to Clavalanic acid 125mg.

Indications:
Amoxicilin and Clavulanate Potassium is indicated for treatment of the following bacterial inlections due to susceptible organisms:
-Upper respiratory tract infection (including ENT) , e.g. tonsillitis, sinusitis, otitis media;
-Lower respiratory tract infections, e.g. actue and chronic bronchitis, lobar and bronchopneumonia.
-Gentio-urinary tract infection, e.g. cystitis, urethritis, pyelonephritis, pelvic infection, chancroid, gonorrhoea.
-Skin and soft tissue infection, e.g. boils, abscesses, cellulitis, animal bites, wound infections.
-Bone and joint infections, e.g. osteomyelitis

Dosage and Administration:
Amoxiclin and Clavulanate Potassiummay be administrated without regards to meals. However, to munimize potential pastrointestinal intolerance, administer at the start of a meal.

Adults and Children over 12 years:
Mild-Moderate infections: One Amoxilln and Clavulanate Potassium 375mg tablet every 8 hours.
Severe infections: One Amoxiclin and Clavulanate Potassium 625mg tablet every 8 hours or one 1g tablet every 12 hours.
Severe dental infections( but not generally first-line): one KONN  One Amoiclin and Clavulanate Potassium 375mg tablet every 8hour lor 5 days.

Drug interaction:
Prolongation of bleeding time and prothrombin time have been reported in some patients receving amoxicilin clavulanic acid. Amoxicilin and Clavulanate Potassium should be used with care in patients on anti-coagulant therapy,in common with other broad-spectrum antibiotics, Amoxiciln and Clavulanate Potassium may reduce the efficacy of oral contraceptives and patients should be wamed accordingly.

Storage:
Store at room temperature below 30c, in a dry place, protected from light.

Testing termsStandardsResults
IdentificationThe retention times of the major peaks    
of the Sample solution correspond to
those of the Standard solution.
Complies
Water≤11.0%9.2%
Weight variationMeet the requirementComplies
Dissolution  RateNLT 85% of the labeled amount of
C16H19N3O5S   and   NLT   80%   of   the   labeled
amount of C8H9NO5.
C16H19N3O5S:
96%  100%  100% 99%  100%  100%
C8H9NO5:
92% 98% 97% 97% 98% 98%
Microbiological
quality
Total aerobe count≤10³cfu/g
The total combined molds and yeasts count≤10²cfu/g
Absence of Escherichia coli
<10cfu/g
<10cfu/g
Negative
AssayAmoxicillin and Clavulanate Potassium              
Tablets contain the equivalent of NLT 90.0%   98.5%
and   NMT    120.0%    of   the    labeled    amount
of amoxicillin(C16H19N3O5S) and clavulanic
acid(C8H9NO5).
C16H19N3O5S:
99.5%
C8H9NO5:
98.5%
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