Omeprazole (omeprazole) is a proton pump inhibitor used to treat peptic ulcer and gastroesophageal reflux disease (GERD) and other diseases. The active form of sulfonamide is then irreversibly combined with the sulfhydryl group of the proton pump through a disulfide bond to form a complex of sulfenamide and proton pump (H+-K+-ATPase), thereby inhibiting the enzyme activity and making the parietal cell H+ cannot be transported into the gastric cavity, blocking the final step of gastric acid secretion in Chemicalbook can greatly reduce the amount of gastric acid in gastric juice. Therefore, this product has a strong and long-lasting inhibitory effect on gastric acid secretion caused by various reasons (such as basal gastric acid secretion and gastric acid secretion caused by histamine, pentagastrin and stimulation of the vagus nerve, including H2 receptor blockers that cannot Inhibition of gastric acid secretion by dibutyl cyclic adenosine monophosphate). This has something to do with the irreversible inhibitory effect of this product on the proton pump, and the acid secretion can only be restored after the formation of a new proton pump.
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Product Name: | Omeprazole | Assay: | 99% |
Appearance: | White crystalline powder | CAS NO: | 73590-58-6 |
Formula: | C17H19N3O3S | Molecular weight: | 345.42 |
EINECS: | 615-996-8 | Application: | pharmaceutical intermediate |
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Application:
1. For gastric and duodenal ulcers, stress ulcers, etc.
2. For reflux esophagitis and gastrinoma.
3. The injection of this product can also be used for:
Gastrointestinal bleeding, such as peptic ulcer bleeding, anastomotic ulcer bleeding, etc., and prevention of upper gastrointestinal bleeding caused by severe diseases (such as cerebral hemorrhage, severe trauma, etc.) and gastric surgery.
Acute gastric mucosal injury complicated by stress or caused by non-steroidal anti-inflammatory drugs.
After general anesthesia or major surgery and comatose patients, to prevent acid reflux and aspiration pneumonia.
4. Combined with amoxicillin and clarithromycin, or metronidazole and clarithromycin, it can effectively kill Helicobacter pylori (Hp)
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