Complaint
· With age, the body's HA decreases. Oral health products containing hyaluronic acid can supplement the body's HA, have the effects of delaying aging and moisturizing the skin, and have been widely used in Japan, the United States and other countries. Hyaluronic acid has been used in eye drops, surgical materials and injections in medicine.
1) increase skin elasticity, postpone skin aging.
2)promote the proliferation and differentiation of epidermal cells, removal of oxygen free radicals,
3)prevent and repair skin damage. Hyaluronic acid aqueous solution has high viscosity
4)make the water phase thickening; And paste evenly after the oil phase emulsification is exquisite, has the stable emulsification. Hyaluronic acid is one of the best natural moisturizing ingredients of high-end cosmetics, good compatibility
5)Can be added to almost any beauty cosmetics, widely used in cream, lotion, lotion, essence, cleansers, bath, wash hair, moss, expansion, lipstick and other cosmetics, general content is 0.05-0.5%.
1. Food Grade
2. Cosmetic Grade
3. Eyedrops Grade(Pharm Grade)
4. Injection Grade(Pharm Grade)
1. Food supplements:| Specification\Name | Food Grade Hyaluronic Acid |
| Characters | White or straw yellow powder |
| Hyaluronic Acid (dry basis) | 90%-105% |
| Glucuronic acid | ≥42.0% |
| PH(0.1% Water Solution) | 6.0-8.0 |
| Molecular Weight | (0.8-2.0)*106 |
| Protein | ≤ 0.1% |
| Transparency (0.1% Solution) | ≥99% |
| Residue on Ignition | ≤20 |
| Loss on drying | ≤10.0% |
| Heavy metals (as Pb) | ≤ 20ppm |
| Arsenic | ≤2ppm |
| Bacteria count | ≤ 100CFU/g |
| Mold & Yeast | ≤10CFU/g |
| Salmonella | Negative |
| Escherichia coli | Negative |
| v | |||
| Items | Specifications | ||
| Cosmetic Grade HA (Low Molecular Weight ) | Cosmetic Grade HA (Middle Molecular Weight ) | Cosmetic Grade HA (High Molecular Weight ) | |
| Characters | White or off-white powder | White or off-white powder | White or off-white powder |
| Hyaluronic Acid (dry basis) | 90%-105% | 90%-105% | 90%-105% |
| PH(0.1% Water Solution) | 6.0-7.5 | 6.0-7.5 | 6.0-7.5 |
| Molecular Weight | 10K Da - 1,000K Da | 1,000K Da - 1,800K Da | ≥1,800K Da |
| Glucuronic acid | ≥45.0% | ≥45.0% | ≥45.0% |
| Protein | ≤0.08% | ≤0.08% | ≤0.08% |
| Heavy metals (as Pb) | ≤20ppm | ≤20ppm | ≤20ppm |
| Loss on drying | ≤10.0% | ≤10.0% | ≤10.0% |
| Residue on Ignition | ≤20 | ≤20 | ≤20 |
| Bacteria count | ≤100cfu/g | ≤100cfu/g | ≤100cfu/g |
| Mold & Yeast | ≤10cfu/g | ≤10cfu/g | ≤10cfu/g |
| Salmonella | Negative | Negative | Negative |
| Escherichia coli | Negative | Negative | Negative |
1). Used in eye surgery, such as corneal transplantation, cataract surgery, glaucoma surgery, and surgery to repair retinal detachment.
| Specification\Name | Eye Drop Grade Hyaluronic Acid |
| Characters | White hygroscopic powder or granule |
| Hyaluronic Acid (dry basis) | 90%-105% |
| Glucuronic acid | ≥45.0% |
| PH(0.1% Water Solution) | 6.0-7.5 |
| Molecular Weight | (0.8-2.0)*106 |
| Intrinsic viscosity | ≥1600(on the dries basis ) |
| Residue on Ignition | ≤20% |
| Protein | ≤0.1% |
| Transparency (0.1% Solution) | ≥99% |
| Loss on drying | ≤8.0% |
| Heavy metals (as Pb) | ≤ 20ppm |
| Arsenic | ≤2ppm |
| Bacteria Endotoxin | ≤0.5 EU/mg |
| Hemolysis | Negative |
| Viable Hemolytical Streptococci | Negative |
| Bacteria count | ≤10CFU/g |
| Mold & Yeast | ≤10CFU/g |
| Pseudomonas aeruginosa | Negative |
