Product name: Carprofen |
Other Name: Imadyl,Rimadyl |
Appearance:White powder |
CAS:53716-49-7 |
M.F.:C15H12ClNO2 |
M.W.:273.71 |
Specification:99% |
Chinese alias (+/-)-6-chloro-alpha-methylcarbazole-2-acetic acid, English name: Carprofen, this product is a white crystalline powder. It is easily soluble in aceton or ethyl acetat, easily soluble in sodium hydroxid or sodium carbonat, and almost insoluble in water.
ITEM | SPECIFICATION | RESULT | METHOD |
Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
Specific Optical | -2.4°~ -2.8° | -2.72° | |
Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
pH | 4.5~7.0 | 5.10 | |
Related substance | Spot not bigger than standard solution spot | No spot | TLC |
Water Content | ≤2% | 0.26% | KF |
Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
This product has strong anti-inflammatory, analgesic and antipyretic effects. The effect is obviously stronger than that of aspirin, phenylbutazone, acetaminophen and ibuprofen. It also has the characteristics of fast absorption and low side effects. The mechanism of action is to inhibit the synthesis of prostaglandins and block inflammatory mediators.