Veterinary API GMP Hot Sale Potassium Clavulanate with Silicon Dioxide (1: 1)

Product Name: Potassium Clavulanate with Silicon Dioxide (1:1).
Formula: Potassium Clavulanate: C8H8KNO5 Silicon dioxide: SiO2
Molecular Weight: Potassium Clavulanate: 237.25 Silicon dioxide: 60.08
CAS Number: Potassium Clavulanate:61177-45-5 Silicon Dioxide: 112926-00-8
Packing:25kg/drum
Specification: EP
MF:C8H10KNO5
MW:239.2

Description:Potassium clavulanate is a semi-synthetic beta-lactamase inhibitor isolated from Streptomyces. The compound contains a beta-lactam ring and strongly binds to beta-lactamase at their new active site, which protects other beta-lactam antibiotics such as amoxicillin from beta-lactamase catalysis.

Uses: Combination of potassium clavulanate and amoxicillin is normally used in medicine to treat numerous different infections caused by bacteria, for instance, pneumonia, sinusitis, ear infections, urinary tract infections, bronchitis, and skin infections. Potassium clavulanate can also combined with other penicillin-based antibiotics.
Clavulanic Acid is a β-lactamase inhibitor, typically added to amoxicillin to increase its effectiveness.
Clavulanic acid is a β-lactam antibiotic produced by several species of Streptomyces. The free acid degrades and is isolated and maintained as either the sodium or potassium salt. Clavulanate is a weak antibiotic, but is a potent inhibitor of β-lactamases. In combination with penicillin and cephalosporins, it shows potent synergistic activity. Clavulanic acid is a suicide inhibitor, covalently binding to a serine residue in the active site of the β-lactamase.

Cautions: Before taking a combination of potassium clavulanate with any other penicillin-based antibiotic, one should discuss with medical providers and let them know whether they have severe kidney disease, jaundice or liver problems. In addition, it is important to inform the physician if an individual is allergic to penicillin or cephalosporin antibiotic, such as Amoxil, Levaquin, omnicef, and cefzil.

Although it is not clear with this drug may harm an unborn baby, it is important to inform the physician if one is pregnant or intending to become pregnant. In addition, studies have indicated that pass into breast milk, thus may affect a nursing infant. As such, it is important to inform the doctor if one is breast-feeding. Children should never be given potassium clavulanate without consulting a physician.

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