Product Name:Chlorhexidine Diacetate CAS:56-95-1 MF:C26H38Cl2N10O4 MW:625.55 EINECS:200-302-4 Mol File:56-95-1.mol Melting point:153-156°C storage temp. 2-8°C solubility H2O: 15 mg/mL, clear form neat Water Solubility 1.9 g/100 mL (20 ºC) Merck 14,2091
Chlorhexidine Diacetate is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque. Chlorhexidine is a cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is effective on both Gram-positive and Gram-negative bacteria, although it is less effective with some Gram-negative bacteria. It has both bactericidal and bacteriostatic mechanisms of action. Aqueous solutions of chlorhexidine are most stable within the pH range of 5-8. Above pH 8.0 chlorhexidine base is precipitated and in more acid conditions there is gradual deterioration of activity because the compound is less stable. Chlorhexidine is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.
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