Complaint
Monobutyrin -- a good source of butyric acid in animals
Butyric acid is the primary source of energy for intestinal cells, but the smell of butyric acid is unpleasant and it is not suitable to be added in large quantities in feed. Tributyrin is an esterification product of 3 molecules of butyric acid and 1 molecule of glycerol.
After monobutyrin reaches the hindgut, it is decomposed into butyric acid under the action of microorganisms to provide energy for the hindgut mucosal cells, promote the development and maturation of the intestinal mucosa, repair the intestinal mucosal damage caused by various stresses, improve intestinal health, improve feed utilization, and improve production performance.
The functional difference of different butyric acid products
| Efficacy | Monobutyrin | Sodium butyrate | Coated Sodium Butyrate | Clostridium butyricum |
| Promote intestinal development | √ | √ | √ | × |
| Promote the proliferation and differentiation of intestinal epithelial cells | √ | × | ||
| Direct energy supply | √ | √ | √ | No report |
| Improve immunity | √ | √ | √ | √ |
| Absorption site | Mainly in the hindgut, Partially absorbed in the small intestine | Complete absorption in the small intestine | Absorbed in the small intestine | Produced only in small amounts in the hindgut |
| Absorption efficiency | Naturally occurring ingredients, High absorption efficiency | Passing the stomach affects efficiency | Coating technology determines efficiency, Uncertain effect | Produced by fermentation, Small amount |
| stability | Stable molecular structure, Pure product without peculiar smell | Easily volatile, strong smell | Weak smell | Butyric acid supply Can not guarantee |
Application in animal nutrition
| Animals | Cycle | Dosage | Results | References |
| Qingyuan partridge broilers | 8 weeks | 250mg/kg MB | Supplementation of monobutyrin increased egg weight, improved egg quality and tended to decrease egg breaking rate of Qingyuan partridge chickens. | Feng et al. 2021 |
| one-day-old Ross 308 male broilers | 5 weeks | 1000ppm MB | Dietary butyrate glycerides can have a significant effect on lipid metabolism and deposition, and breast muscle deposition; Monobutyrin and tributyrin could act synergistically to improve animal performance. | Bedford et al. 2017 |
| Pacific white shrimp | 53 days | 2g/kg MB | Dietary supplementation of 2 g/kg MB or 1-2 g/kg TB can improve growth and feed efficiency, innate immunity, antioxidant activity, digestibility and disease resistance of L. vannamei. | Lee et al. 2021 |
| Salmonella Typhimurium and Clostridium perfringens | In Vitro Trials | MB | the higher inhibitory effect by 50% monobutyrin for Salmonella Typhimurium and C. perfringens in the culture containing intestinal contents, Butyrate monoglyceride has the added advantage of being water soluble. | Wang et al. 2019 |
| Name | Content | Recommened dosage | Pack size | Storage | Sanitary standards | Notes |
| Monobutyrin | Glyceryl Butyrate ≥ 50% Water ≤ 5% | Swine: 0.5-2.0 kg/ton Poultry: 0.3-1.0 kg/ton Aquatic: 1.0-3.0 kg/ton | 25 kg/bag | Store in dry and cool place, shelf life: 24 months | Pb ≤ 5.0 mg/kg As ≤ 5.0 mg/kg | Carrier: Silica Tons: represent complete feed |
